Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Aug;35(3):141-144.
doi: 10.1055/s-0041-1731791. Epub 2021 Jul 15.

Wound Healing: A Comprehensive Review

Affiliations
Review

Wound Healing: A Comprehensive Review

Yasser H Almadani et al. Semin Plast Surg. 2021 Aug.

Abstract

Wound healing is an intricate, tightly regulated process that is critical to maintaining the barrier function of skin along with preserving all other skin functions. This process can be influenced by a variety of modifiable and nonmodifiable factors. As wound healing takes place in all parts of the human body, this review focuses on cutaneous wound healing and highlights the classical wound healing phases. Alterations in any of these phases can promote chronic wound development and may impede wound healing.

Keywords: chronic wounds; inflammation; wound healing.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None declared.

References

    1. Swann G. The skin is the body's largest organ. J Vis Commun Med. 2010;33(04):148–149. - PubMed
    1. Nussbaum S R, Carter M J, Fife C E. An economic evaluation of the impact, cost, and medicare policy implications of chronic nonhealing wounds. Value Health. 2018;21(01):27–32. - PubMed
    1. Sen C K. Human wounds and its burden: an updated compendium of estimates. Adv Wound Care (New Rochelle) 2019;8(02):39–48. - PMC - PubMed
    1. Chhabra S, Chhabra N, Kaur A, Gupta N. Wound healing concepts in clinical practice of OMFS. J Maxillofac Oral Surg. 2017;16(04):403–423. - PMC - PubMed
    1. Al-Khamis A, McCallum I, King P M, Bruce J. Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst Rev. 2010;2010(01):CD006213. - PMC - PubMed