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Review
. 2021 Aug;35(3):153-158.
doi: 10.1055/s-0041-1731460. Epub 2021 Jul 15.

Updates in Diabetic Wound Healing, Inflammation, and Scarring

Nina Dasari  1 , Austin Jiang  1 , Anna Skochdopole  1 , Jayer Chung  2 , Edward M Reece  1   3 , Joshua Vorstenbosch  4 , Sebastian Winocour  1
Affiliations
Review

Updates in Diabetic Wound Healing, Inflammation, and Scarring

Nina Dasari et al. Semin Plast Surg. 2021 Aug.

Abstract

Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.

Keywords: diabetes; inflammation; scarring; wound healing.

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Conflict of interest statement

Conflict of Interest None declared.

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