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. 2021 Aug;94(Suppl No 1):S25-S27.
doi: 10.15386/mpr-2223. Epub 2021 Aug 10.

Cardiovascular manifestations in Marfan syndrome

Cecilia Lazea  1   2 , Simona Bucerzan  1   2 , Mirela Crisan  2 , Camelia Al-Khzouz  1   2 , Diana Miclea  1   2 , Crina Şufană  2 , Gabriel Cismaru  1   3 , Paula Grigorescu-Sido  1
Affiliations

Cardiovascular manifestations in Marfan syndrome

Cecilia Lazea et al. Med Pharm Rep. 2021 Aug.

Abstract

Marfan syndrome (MFS) is an autosomal dominant inherited disease of the connective tissue with multiorgan involvement (skeleton, cardiovascular, eyes, skin, lungs). Cardiovascular involvement is variable and represents the major cause of morbidity and mortality in Marfan syndrome. We provide a comprehensive description of cardiovascular manifestations in Marfan syndrome, genotype-phenotype correlations and assessment of cardiovascular abnormalities and complications.

Keywords: Marfan syndrome; cardiovascular diseases.

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