Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec;12(12):2112-2123.
doi: 10.1111/jdi.13668. Epub 2021 Oct 3.

Epidemiological characteristics of diabetic kidney disease in Taiwan

Jun-Sing Wang  1   2   3   4 , Fu-Shun Yen  5 , Kun-Der Lin  6   7 , Shyi-Jang Shin  7   8 , Yueh-Han Hsu  9   10 , Chih-Cheng Hsu  11   12   13 ; Diabetes Kidney Disease Research Committee of the Diabetes Association of the Republic of China (Taiwan)
Affiliations
Review

Epidemiological characteristics of diabetic kidney disease in Taiwan

Jun-Sing Wang et al. J Diabetes Investig. 2021 Dec.

Abstract

Diabetic kidney disease (DKD) is a critical microvascular complication of diabetes. With the continuous increase in the prevalence of diabetes since 2000, the prevalence of DKD has also been increasing in past years. The prevalence of DKD among individuals with type 2 diabetes in Taiwan increased from 13.32% in 2000 to 17.92% in 2014. The cumulative incidence of DKD among individuals with type 1 diabetes in Taiwan was higher than 30% during 1999-2012. DKD is the leading cause of end-stage renal disease (ESRD), with a prevalence of approximately 45% in a population on chronic dialysis in Taiwan. Among individuals with type 2 diabetes, the prevalence of ESRD in the receipt of dialysis also increased from 1.32% in 2005 to 1.47% in 2014. Risk factors for DKD development are age, race, family history, hyperglycemia, hypertension, dyslipidemia, dietary patterns, and lifestyles. Prognostic factors that aggravate DKD progression include age, family history, sex, glycemic control, blood pressure (BP), microvascular complications, and atherosclerosis. This review summarizes updated information on the onset and progression of DKD, particularly in the Taiwanese population. Translating these epidemiological features is essential to optimizing the kidney care and improving the prognosis of DKD in Asian populations.

Keywords: Diabetic kidney disease; Prognostic factors; Risk factors.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Rates of progression from diabetes mellitus (DM) to diabetic kidney disease (DKD), end stage renal disease (ESRD), cardiovascular disases, and death.
See this image and copyright information in PMC

References

    1. Institute for Health Metrics and Evaluation, Global Health Data Exchange, Global Burden of Disease Study 2019 (GBD 2019) Data resources, GBD results tool, terms and conditions. 2019. Available from: http://ghdx.healthdata.org/gbd‐results‐tool Assessed August 13, 2021.
    1. Parving H‐H, Lewis JB, Ravid M, et al. Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective. Kidney Int 2006; 69: 2057–2063. - PubMed
    1. Taiwan Society of Nephrology . 2019 Annual Report on Kidney Disease in Taiwan. Available from: https://www.tsn.org.tw/enVersion/TWRDS.aspx Accessed April 6, 2021.
    1. Couser WG, Remuzzi G, Mendis S, et al. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int 2011; 80: 1258–1270. - PubMed
    1. Adler AI, Stevens RJ, Manley SE, et al. Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int 2003; 63: 225–232. - PubMed