A Host of Host Assays: The Clinical Accuracy of Two Host Gene Expression Assays in Acute Infection
- PMID: 34529611
- DOI: 10.1097/CCM.0000000000005220
A Host of Host Assays: The Clinical Accuracy of Two Host Gene Expression Assays in Acute Infection
Conflict of interest statement
The authors have disclosed that they do not have any potential conflicts of interest.
Comment on
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Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test.Crit Care Med. 2021 Oct 1;49(10):1651-1663. doi: 10.1097/CCM.0000000000005085. Crit Care Med. 2021. PMID: 33938716 Free PMC article.
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A Novel 29-Messenger RNA Host-Response Assay From Whole Blood Accurately Identifies Bacterial and Viral Infections in Patients Presenting to the Emergency Department With Suspected Infections: A Prospective Observational Study.Crit Care Med. 2021 Oct 1;49(10):1664-1673. doi: 10.1097/CCM.0000000000005119. Crit Care Med. 2021. PMID: 34166284 Free PMC article.
References
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- Heffernan AJ, Denny KJ: Host diagnostic biomarkers of infection in the ICU: Where are we and where are we going? Curr Infect Dis Rep. 2021; 23:4
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- Kwok AJ, Mentzer A, Knight JC: Host genetics and infectious disease: New tools, insights and translational opportunities. Nat Rev Genet. 2021; 22:137–153
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- Tsalik EL, Henao R, Montgomery JL, et al.; Antibacterial Resistance Leadership Group: Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test. Crit Care Med. 2021; 49:1651–1663
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- Bauer W, Kappert K, Galtung N, et al.: A Novel 29-Messenger RNA Host-Response Assay From Whole Blood Accurately Identifies Bacterial and Viral Infections in Patients Presenting to the Emergency Department With Suspected Infections: A Prospective Observational Study. Crit Care Med. 2021; 49:1664–1673
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- Tsalik EL, Henao R, Nichols M, et al.: Host gene expression classifiers diagnose acute respiratory illness etiology. Sci Transl Med. 2016; 8:322ra11
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