Seeing Interventions in a Favorable Light: The Consequences of Unblinded Trials
- PMID: 34529618
- DOI: 10.1097/CCM.0000000000005109
Seeing Interventions in a Favorable Light: The Consequences of Unblinded Trials
Conflict of interest statement
Dr. Yarnell has disclosed that he does not have any potential conflicts of interest.
Comment on
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Association Between Lack of Blinding and Mortality Results in Critical Care Randomized Controlled Trials: A Meta-Epidemiological Study.Crit Care Med. 2021 Oct 1;49(10):1800-1811. doi: 10.1097/CCM.0000000000005065. Crit Care Med. 2021. PMID: 33927122
References
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- Moher D, Hopewell S, Schulz KF, et al.: CONSORT 2010 explanation and elaboration: Updated guidelines for reporting parallel group randomised trials. BMJ. 2010; 340:c869
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- Martin GL, Trioux T, Gaudry S, et al.: Association Between Lack of Blinding and Mortality Results in Critical Care Randomized Controlled Trials: A Meta-Epidemiological Study. Crit Care Med. 2021; 49:1800–1811
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- Anand R, Norrie J, Bradley JM, et al.: Fool’s gold? Why blinded trials are not always best. BMJ. 2020; 368:l6228
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- Yarnell CJ, Abrams D, Baldwin MR, et al.: Clinical trials in critical care: Can a Bayesian approach enhance clinical and scientific decision making?. Lancet Respir Med. 9:207–216
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