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Editorial
. 2022 Feb 10;59(2):2102076.
doi: 10.1183/13993003.02076-2021. Print 2022 Feb.

Convalescent plasma for SARS-CoV-2 infection: win or learn

Enric Contreras-Barbeta  1 , Anna Millan  1 , Jordi Rello  2   3   4
Affiliations
Editorial

Convalescent plasma for SARS-CoV-2 infection: win or learn

Enric Contreras-Barbeta et al. Eur Respir J. .

Abstract

Current evidence does not support the use of convalescent plasma in the standard therapy for COVID-19 https://bit.ly/3DGyz6t

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: E. Contreras-Barbeta has nothing to disclose. Conflict of interest: A. Millan has nothing to disclose. Conflict of interest: J. Rello has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Emil Adolf von Behring and anti-diphtheria serum.
See this image and copyright information in PMC

Comment on

  • Convalescent plasma for COVID-19 in hospitalised patients: an open-label, randomised clinical trial.
    Sekine L, Arns B, Fabro BR, Cipolatt MM, Machado RRG, Durigon EL, Parolo E, Pellegrini JAS, Viana MV, Schwarz P, Lisboa TC, Dora JMS, Portich JP, Paz AA, Silla L, Balsan AM, Schirmer FD, Franz JPM, da-Silveira LM, Breunig RC, Petersen V, Sosnoski M, Mesquita NF, Volpato FCZ, Sganzerla D, Falavigna M, Rosa RG, Zavascki AP; PLACOVID Study Group. Sekine L, et al. Eur Respir J. 2022 Feb 10;59(2):2101471. doi: 10.1183/13993003.01471-2021. Print 2022 Feb. Eur Respir J. 2022. PMID: 34244316 Free PMC article. Clinical Trial.
  • Early high antibody titre convalescent plasma for hospitalised COVID-19 patients: DAWn-plasma.
    Devos T, Van Thillo Q, Compernolle V, Najdovski T, Romano M, Dauby N, Jadot L, Leys M, Maillart E, Loof S, Seyler L, Moonen M, Moutschen M, Van Regenmortel N, Ariën KK, Barbezange C, Betrains A, Garigliany M, Engelen MM, Gyselinck I, Maes P, Schauwvlieghe A, Liesenborghs L, Belmans A, Verhamme P, Meyfroidt G; DAWn-plasma investigators. Devos T, et al. Eur Respir J. 2022 Feb 10;59(2):2101724. doi: 10.1183/13993003.01724-2021. Print 2022 Feb. Eur Respir J. 2022. PMID: 34446469 Free PMC article. Clinical Trial.

References

    1. Soo YO, Cheng Y, Wong R, et al. . Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients. Clin Microbiol Infect 2004; 10: 676–678. doi:10.1111/j.1469-0691.2004.00956.x - DOI - PMC - PubMed
    1. Cheng Y, Wong R, Soo YO, et al. . Use of convalescent plasma therapy in SARS patients in Hong Kong. Eur J Clin Microbiol Infect Dis 2005; 24: 44–46. doi:10.1007/s10096-004-1271-9 - DOI - PMC - PubMed
    1. Shen CH, Wang Z, Zhao F, et al. . Treatment of 5 critically ill patients with COVID-19 with convalescent plasma. JAMA 2020; 323: 1582–1589. doi:10.1001/jama.2020.4783 - DOI - PMC - PubMed
    1. Duan K, Liu B, Li C, et al. . The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study. medRXiv 2020; preprint [10.1101/2020.03.16.20036145]. - DOI - PubMed
    1. European Commission Directorate-General for Health and Food Safety . An EU programme of COVID-19 convalescent plasma collection and transfusion: guidance on collection, testing, processing, storage, distribution and monitored use. 2021. https://ec.europa.eu/health/sites/default/files/blood_tissues_organs/doc....

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