Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Nov;44(11):e192-e193.
doi: 10.2337/dc21-0939. Epub 2021 Sep 16.

Hyperglycemia Drives Stent Restenosis in STEMI Patients

Pasquale Mone  1   2   3 , Jessica Gambardella  4   5   6 , Fabio Minicucci  7 , Angela Lombardi  4 , Ciro Mauro  7 , Gaetano Santulli  1   5   6
Affiliations

Hyperglycemia Drives Stent Restenosis in STEMI Patients

Pasquale Mone et al. Diabetes Care. 2021 Nov.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
A: Kaplan-Meier curves assessing the cumulative risk of restenosis in patients with ST-elevation myocardial infarction (STEMI) from hospital admission to 365 days; patients were subdivided into three groups: normoglycemic (NG) subjects, patients without diabetes mellitus (DM) but with hyperglycemia HG (HG-non-DM), and patients with both HG and DM (HG-DM). B: Multivariate Cox regression analysis in STEMI HG-non-DM patients. BMI, body mass index; CI, confidence interval; DBP, diastolic blood pressure; HbA1c, hemoglobin A1c (glycated hemoglobin); HR, hazard ratio; LDL, low-density lipoprotein; SBP, systolic blood pressure.
See this image and copyright information in PMC

References

    1. Zarich SW, Nesto RW. Implications and treatment of acute hyperglycemia in the setting of acute myocardial infarction. Circulation 2007;115:e436–e439 - PubMed
    1. Marfella R, Sasso FC, Siniscalchi M, et al. Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction. J Clin Endocrinol Metab 2012;97:2862–2871 - PubMed
    1. American Diabetes Association . 15. Diabetes care in the hospital: Standards of Medical Care in Diabetes–2021. Diabetes Care 2021;44(Suppl. 1):S211–S220 - PubMed
    1. Santulli G, Wronska A, Uryu K, et al. A selective microRNA-based strategy inhibits restenosis while preserving endothelial function. J Clin Invest 2014;124:4102–4114 - PMC - PubMed
    1. Roberts GW, Quinn SJ, Valentine N, et al. Relative hyperglycemia, a marker of critical illness: Introducing the stress hyperglycemia ratio. J Clin Endocrinol Metab 2015;100:4490–4497 - PubMed

Publication types