Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jul 20;9(9):5293-5311.
doi: 10.1002/fsn3.2475. eCollection 2021 Sep.

The effects of ginseng on the metabolic syndrome: An updated review

Tahereh Aminifard  1 , Bibi Marjan Razavi  1   2 , Hossein Hosseinzadeh  1   3
Affiliations
Review

The effects of ginseng on the metabolic syndrome: An updated review

Tahereh Aminifard et al. Food Sci Nutr. .

Abstract

Metabolic syndrome is a group of risk factors including high blood glucose, dyslipidemia, high blood pressure, and high body weight. It can increase the risk of diabetes and cardiovascular disorders, which are the important reasons for death around the world. Nowadays, there are numerous demands for herbal medicine because of less harmful effects and more useful effects in comparison with chemical options. Ginseng is one of the most famous herbs used as a drug for a variety of disorders in humans. The antihyperlipidemia, antihypertension, antihyperglycemic, and anti-obesity effects of ginseng and its active constituents such as ginsenosides have been shown in different studies. In this review article, the different in vitro, in vivo, and human studies concerning the effects of ginseng and its active constituents in metabolic syndrome have been summarized. According to these studies, ginseng can control metabolic syndrome and related diseases.

Keywords: Panax ginseng; diabetes; ginseng; herbal medicine; hypertension; metabolic syndrome.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Some of the pharmacologically active constituents of ginseng
FIGURE 2
FIGURE 2
Schematic effects of ginseng in metabolic syndrome
See this image and copyright information in PMC

References

    1. Akaberi, M., & Hosseinzadeh, H. (2016). Grapes (Vitis vinifera) as a potential candidate for the therapy of the metabolic syndrome. Phytotherapy Research, 30(4), 540–556. - PubMed
    1. Akdoğan, M., Nasır, Y., Cengİz, N., & Bİlgİlİ, A. (2018). The effects of milled Tribulus terrestris, Avena sativa, and white ginseng powder on total cholesterol, free testosterone levels and testicular tissue in rats fed a high‐cholesterol diet. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 65(3), 267–272. 10.1501/Vetfak_0000002856 - DOI
    1. Arab, E., Ezz, A., El‐Mahdy, A., & Abbas, O. (2016). Nigella sativa and Panax ginseng supplementation ameliorate induced‐hyperlipidemia in male rats. Arab Journal of Nuclear Sciences and Applications, 49(3), 237–249.
    1. Arafa, R. M. (2013). Influence of ginseng, curcumin and their combination on rats suffering from diabetes and acute liver diseases. World Applied Sciences Journal, 26, 1391–1399. 10.5829/idosi.wasj.2013.26.10.13576 - DOI
    1. Ayaz, N. O., & Alnahdi, H. S. (2018). Potential impact of Panax ginseng against ethanol induced hyperlipidemia and cardiac damage in rats. Pakistan Journal of Pharmaceutical Sciences, 31(3), 927–932. - PubMed

LinkOut - more resources