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Editorial
. 2021 Nov;69(11):3071-3073.
doi: 10.1111/jgs.17443. Epub 2021 Sep 17.

Do the telomere ends justify the physical means?

Robert J Pignolo  1 , F Brad Johnson  2
Affiliations
Editorial

Do the telomere ends justify the physical means?

Robert J Pignolo et al. J Am Geriatr Soc. 2021 Nov.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors declare no conflicts.

Figures

Figure 1.
Figure 1.
Potential relationships between telomere status and physical activity. (A) Possible mechanisms by which physical activity (PA) may abrogate telomere dysfunction (i.e. maintain capping). (B) Telomere attrition (TA) may be inversely related to PA but limitations to confirming this association include multiple confounders. (C) Middle-aged athletes may reap the most benefit from physical activity, in terms of TL maintenance.
See this image and copyright information in PMC

Comment on

References

    1. Telomeres Mendelian Randomization C, Haycock PC, Burgess S, et al. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol. 2017;3(5):636–651. - PMC - PubMed
    1. Valente C, Andrade R, Alvarez L, Rebelo-Marques A, Stamatakis E, Espregueira-Mendes J. Effect of physical activity on telomere length: Systematic review with meta-analysis. Journal of the American Geriatrics Association. 2021. - PubMed
    1. Ornish D, Lin J, Daubenmier J, et al. Increased telomerase activity and comprehensive lifestyle changes: a pilot study. Lancet Oncol. 2008;9(11):1048–1057. - PubMed
    1. Cash SW, Beresford SA, Vaughan TL, et al. Recent physical activity in relation to DNA damage and repair using the comet assay. J Phys Act Health. 2014;11(4):770–776. - PMC - PubMed
    1. Vina J, Rodriguez-Manas L, Salvador-Pascual A, Tarazona-Santabalbina FJ, Gomez-Cabrera MC. Exercise: the lifelong supplement for healthy ageing and slowing down the onset of frailty. J Physiol. 2016;594(8):1989–1999. - PMC - PubMed