Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Oct 8;39(42):6195-6200.
doi: 10.1016/j.vaccine.2021.09.004. Epub 2021 Sep 4.

Myocarditis following COVID-19 vaccination - A case series

Dan Levin  1 , Gil Shimon  2 , Maggie Fadlon-Derai  2 , Liron Gershovitz  2 , Amiram Shovali  2 , Anat Sebbag  2 , Shakib Bader  2 , Noam Fink  2 , Barak Gordon  3
Affiliations
Comment

Myocarditis following COVID-19 vaccination - A case series

Dan Levin et al. Vaccine. .

Abstract

There have been reports of myocarditis following COVID-19 vaccination. We surveyed all hospitalized military personnel in the Isareli Defense Forces during the period of the COVID-19 vaccination operation (12/28/2021-3/7/2021) for diagnosed myocarditis. We identified 7 cases of myocarditis with symptoms starting in the first week after the second dose of COVID-19 Pfizer-BioNTech vaccine. One case of myocarditis diagnosed 10 days after the second dose of the vaccine was not included. These 8 cases comprise of all events of myocarditis diagnosed in military personnel during this time period. All patients were young and generally healthy. All had mild disease with no sequalae. The incidence of myocarditis in the week following a second dose of the vaccine was 5.07/100,000 people vaccinated. Due to the nature of this report no causality could be established. Clinicians should be aware of the possibility of myocarditis following Pfizer-BioNTech vaccination. True incidence rates should be further investigated.

Keywords: COVID-19; Myocarditis; Vaccines.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Comment on

References

    1. Lala A., Johnson K.W., Januzzi J.L., Russak A.J., Paranjpe I., Richter F., et al. Mount Sinai COVID Informatics Center. Prevalence and Impact of Myocardial Injury in Patients Hospitalized With COVID-19 Infection. J Am Coll Cardiol. 2020;76(5):533–546. PMID: 32517963; PMCID: PMC7279721. - PMC - PubMed
    1. Kawakami R., Sakamoto A., Kawai K., Gianatti A., Pellegrini D., Nasr A., et al. Pathological Evidence for SARS-CoV-2 as a Cause of Myocarditis: JACC Review Topic of the Week. J Am Coll Cardiol. 2021;77(3):314–325. PMID: 33478655; PMCID: PMC7816957. - PMC - PubMed
    1. Bajaj R., Sinclair H.C., Patel K., Low B., Pericao A., Manisty C., et al. Delayed-onset myocarditis following COVID-19. Lancet Respir Med. 2021;9(4):e32–e34. Epub 2021 Feb 19. PMID: 33617781; PMCID: PMC7906752. - PMC - PubMed
    1. Morris S.B., Schwartz N.G., Patel P., Abbo L., Beauchamps L., Balan S., et al. Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection - United Kingdom and United States, March-August 2020. MMWR Morb Mortal Wkly Rep. 2020;69(40):1450–1456. PMID: 33031361; PMCID: PMC7561225. - PMC - PubMed
    1. Marshall M., Ferguson I.D., Lewis P., Jaggi P., Gagliardo C., Collins J.S., Shaughnessya R., Carona R., Fuss C., Corbin K.J.E., Emuren L., Faherty E., Hall E.K., Di Pentima C., Oster M.E., Paintsil E., Siddiqui S., Timchak D.M., Guzman-Cottrill J.A. Symptomatic Acute Myocarditis in Seven Adolescents Following Pfizer-BioNTech COVID-19 Vaccination. Pediatrics. 2021 Epub ahead of print. PMID: 34088762. - PubMed

Substances