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Review
. 2021 Nov:100:102290.
doi: 10.1016/j.ctrv.2021.102290. Epub 2021 Sep 9.

Comparing cancer and cardiovascular disease trends in 20 middle- or high-income countries 2000-19: A pointer to national trajectories towards achieving Sustainable Development goal target 3.4

Affiliations
Review

Comparing cancer and cardiovascular disease trends in 20 middle- or high-income countries 2000-19: A pointer to national trajectories towards achieving Sustainable Development goal target 3.4

Freddie Bray et al. Cancer Treat Rev. 2021 Nov.

Abstract

With the 2030 Sustainable Development Goals (SDG) target of a one-third reduction in noncommunicable diseases (NCDs) less than a decade away, it is timely to assess national progress in reducing premature deaths from the two leading causes of mortality worldwide. We examine trends in the probability of dying ages 30-70 from cardiovascular disease (CVD) and cancer 2000-19 in 10 middle-income (MICs) and 10 high-income (HICs) countries with high quality data. We then predict whether the SDG target will be met in each country for CVD, cancer and for the four main NCDs combined. Downward trends were more evident in HICs relative to the MICs, and for CVD relative to cancer. CVD and cancer declines ranged from 30-60% and 20-30% in HICs over the 20-year period, but progress was less uniform among the MICs. Premature deaths from cancer exceeded CVD in nine of the 10 HICs by 2000 and in all 10 by 2019; in contrast, CVD mortality exceeded cancer in all 10 MICs in 2000 and remained the leading cause in eight countries by 2019. Two of the 10 MICs (Colombia and Kazakhstan) and seven of the HICs (Australia, Chile, Italy, New Zealand, Norway, Slovakia, and the U.K.) are predicted to meet the SDG NCDs target. Whether countries are on course to meet the target by 2030 reflects changing risk factor profiles and the extent to which effective preventative and medical care interventions have been implemented. In addition, lessons can be learned given people living with NCDs are more susceptible to severe COVID-19 illness and death.

Keywords: Cancer; Cardiovascular disease; Epidemiology; Premature mortality; SDGs.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Trends in the unconditional probability of dying between ages 30 and 70 years from cardiovascular diseases and cancer 2000–19 in middle-income (left panel) and high-income countries (right panel). Both sexes. Countries within income group are ordered in terms of increasing probability of dying from cancer in 2019. Source: WHO Global Health Estimates .
Fig. A1
Fig. A1
Trends in the unconditional probability of dying between ages 30 and 70 years from cardiovascular diseases and cancer 2000–19 in middle-income (left panel) and high-income countries (right panel). Males. Countries within income group are ordered in terms of increasing probability of dying from cancer in 2019. Source: WHO Global Health Estimates .
Fig. A2
Fig. A2
Trends in the unconditional probability of dying between ages 30 and 70 years from cardiovascular diseases and cancer 2000–19 in middle-income (left panel) and high-income countries (right panel). Females. Countries within income group are ordered in terms of increasing probability of dying from cancer in 2019. Source: WHO Global Health Estimates .

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