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Review
. 2021 Oct;16(4):597-612.
doi: 10.1016/j.cpet.2021.06.007.

Radiomics in PET Imaging:: A Practical Guide for Newcomers

Fanny Orlhac  1 , Christophe Nioche  2 , Ivan Klyuzhin  3 , Arman Rahmim  3 , Irène Buvat  2
Affiliations
Review

Radiomics in PET Imaging:: A Practical Guide for Newcomers

Fanny Orlhac et al. PET Clin. 2021 Oct.

Abstract

Radiomics has undergone considerable development in recent years. In PET imaging, very promising results concerning the ability of handcrafted features to predict the biological characteristics of lesions and to assess patient prognosis or response to treatment have been reported in the literature. This article presents a checklist for designing a reliable radiomic study, gives an overview of the steps of the pipeline, and outlines approaches for data harmonization. Tips are provided for critical reading of the content of articles. The advantages and limitations of handcrafted radiomics compared with deep-learning approaches for the characterization of PET images are also discussed.

Keywords: Harmonization; Heterogeneity; PET; Radiomics; Texture.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

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