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Review
. 2021 Nov:155:111557.
doi: 10.1016/j.exger.2021.111557. Epub 2021 Sep 17.

Blood pressure, frailty and dementia

Jane A H Masoli  1 , João Delgado  2
Affiliations
Review

Blood pressure, frailty and dementia

Jane A H Masoli et al. Exp Gerontol. 2021 Nov.

Abstract

High blood pressure (BP) affects 75% of people aged over 70. Ageing alters BP homeostasis, resulting in postural hypotension and increased BP variability. Co-morbidity and frailty add complexity to understanding BP changes in later life. Longitudinal BP declines are likely driven by accumulating co-morbidity and are accelerated in both frailty and dementia. This narrative review summarises what is known about the association between BP and frailty, the clinical management of BP in frailty and the association between BP, cognitive decline and dementia.

Keywords: Ageing; Blood pressure; Dementia; Frailty; Hypertension.

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