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. 2021 Dec;83(6):709-737.
doi: 10.1016/j.jinf.2021.09.012. Epub 2021 Sep 16.

Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients

Affiliations

Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients

Andrea Alemany et al. J Infect. 2021 Dec.
No abstract available

Keywords: Nasal; Nasopharyngeal swab; SARS-CoV-2; Saliva; Screening; Viral load.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig 1
Fig. 1
Distribution of RT-qPCR cycle threshold (Ct) of nasopharyngeal swabs, nasal swabs, and saliva specimens collected at baseline (A) and day 7 (B). Cts correspond to the viral RNA-dependent RNA polymerase (RdRP) gene.
Fig 2
Fig. 2
Correlation of the viral load (VL) of nasopharyngeal swabs with that of nasal swabs and saliva specimens at baseline (A) and day 7 (B). Viral loads were estimated using a calibration line obtained with serial dilutions of SARS-CoV-2 control RNA, run in parallel to a set of samples covering all thermal cycles used in the analysis. Negative samples (in red) were assigned to a Ct of 40 (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.).

References

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