Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Oct;15(15):1435-1449.
doi: 10.2217/bmm-2021-0038. Epub 2021 Sep 20.

Prospective selected biomarkers in COVID-19 diagnosis and treatment

Tahani Tabassum  1 , Ahsab Rahman  1 , Yusha Araf  2 , Md A Ullah  3 , Mohammad J Hosen  2
Affiliations

Prospective selected biomarkers in COVID-19 diagnosis and treatment

Tahani Tabassum et al. Biomark Med. 2021 Oct.

Abstract

COVID-19 has become a global health concern, due to the high transmissible nature of its causal agent and lack of proper treatment. Early diagnosis and nonspecific medical supports of the patients appeared to be effective strategy so far to combat the pandemic caused by COVID-19 outbreak. Biomarkers can play pivotal roles in timely and proper diagnosis of COVID-19 patients, as well as for distinguishing them from other pulmonary infections. Besides, biomarkers can help in reducing the rate of mortality and evaluating viral pathogenesis with disease prognosis. This article intends to provide a broader overview of the roles and uses of different biomarkers in the early diagnosis of COVID-19, as well as in the classification of COVID-19 patients into multiple risk groups.

Keywords: COVID-19; biomarkers; detection; prognosis; pulmonary infections; stratification.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Clinical courses of SARS-CoV-2.
The virus enters the body and damages the lungs. Symptoms may vary from person to person.
See this image and copyright information in PMC

References

    1. Coronavirus disease (COVID-19) – World Health Organization. (2020). https://www.who.int/emergencies/diseases/novel-coronavirus-2019
    1. Coronavirus update (live): 46,495,184 cases and 1,201,924 deaths from COVID-19 virus pandemic – Worldometer (2020). https://www.worldometers.info/coronavirus/
    1. Chan J, Kok K, Zhu Zet al.Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg. Microbes Infect. 9(1), 221–236 (2020). - PMC - PubMed

    2. • The authors performed a bioinformatics analysis on the SARS-CoV-2 genome and compared it with other related coronavirus genomes with an aim to exploring the evolution of the novel lineage B betacoronavirus. This article provided a very basic understanding of the pathogenesis of this emerging infectious virus that aided an extensive understanding of the viral pathology.

    1. Hoffmann M, Kleine-Weber H, Schroeder Set al.SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 181(2), 271–280 (2020). - PMC - PubMed
    1. Islam H, Rahman A, Masud Jet al.A generalized overview of SARS-CoV-2: where does the current knowledge stand? Electronic J. Gen. Med. 17(6), em251 (2020).