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. 2021 Sep 3:12:711741.
doi: 10.3389/fimmu.2021.711741. eCollection 2021.

Complication and Sequelae of COVID-19: What Should We Pay Attention to in the Post-Epidemic Era

Keda Yang  1 , Guangfu Wen  2 , Jinpeng Wang  1 , Siming Zhou  1 , Wacili Da  1 , Yan Meng  1 , Yuchuan Xue  3 , Lin Tao  1
Affiliations

Complication and Sequelae of COVID-19: What Should We Pay Attention to in the Post-Epidemic Era

Keda Yang et al. Front Immunol. .

Abstract

COVID-19 is widespread worldwide and seriously affects the daily life and health of humans. Countries around the world are taking necessary measures to curb the spread. However, COVID-19 patients often have at least one organ complication and sequelae in addition to respiratory symptoms. Controlling the epidemic is only a phased victory, and the complication and sequelae of COVID-19 will need more attention in the post-epidemic era. We collected general information from over 1000 articles published in 2020 after the COVID-19 outbreak and systematically analyzed the complication and sequelae associated with eight major systems in COVID-19 patients caused by ACE2 intervention in the RAS regulatory axis. The autoimmune response induced by 2019-nCoV attacks and damages the normal tissues and organs of the body. Our research will help medical workers worldwide address COVID-19 complication and sequelae.

Keywords: COVID-19; Web of Science; bibliometric analysis; complication; eight systems; sequelae.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The distribution of countries/regions. The development of the top 10 countries/regions.
Figure 2
Figure 2
The distribution of countries/regions. The cooperation of countries/regions.
Figure 3
Figure 3
The top ten institutions ranked in terms of the article counts.
Figure 4
Figure 4
The distribution of authors involved in COVID-19 complication and sequelae research. The article counts of the top ten co-cited authors.
Figure 5
Figure 5
The distribution of authors involved in COVID-19 complication and sequelae research. The network map of co-cited authors.
Figure 6
Figure 6
Keywords in publications about COVID-19 complication and sequelae research. (A) Mapping of the keywords into seven clusters with different colors. (B) Distribution of keywords was presented according to the appearance for the average time.
See this image and copyright information in PMC

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