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Editorial
. 2021 Sep 3:12:756087.
doi: 10.3389/fimmu.2021.756087. eCollection 2021.

Editorial: Lessons on T-Cells and Immune-Targeting Therapeutics in Coeliac Disease

Melinda Y Hardy  1   2 , Daniel Agardh  3 , Robert P Anderson  4
Affiliations
Editorial

Editorial: Lessons on T-Cells and Immune-Targeting Therapeutics in Coeliac Disease

Melinda Y Hardy et al. Front Immunol. .
No abstract available

Keywords: T cells; autoimmunity; coeliac disease; dermatitis herpetiformis; prevention; transglutaminase; treatment.

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Conflict of interest statement

RA has served as consultant for Takeda, GSK, Anokion, Allero Therapeutics, Treg Therapeutics, EVOQ Therapeutics, and Bristol-Myers Squibb. He is also founder and shareholder of Novoviah Pharmaceuticals and is the inventor of patents relating to the diagnosis and treatment of coeliac disease. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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  • Editorial on the Research Topic Lessons on T-Cells and Immune-Targeting Therapeutics in Coeliac Disease

References

    1. Sollid LM, Tye-Din JA, Qiao SW, Anderson RP, Gianfrani C, Koning F. Update 2020: Nomenclature and Listing of Celiac Disease-Relevant Gluten Epitopes Recognized by CD4(+) T Cells. Immunogenetics (2020) 72:85–8. 10.1007/s00251-019-01141-w - DOI - PubMed
    1. Hardy MY, Tye-Din JA, Stewart JA, Schmitz F, Dudek NL, Hanchapola I, et al. . Ingestion of Oats and Barley in Patients With Celiac Disease Mobilizes Cross-Reactive T Cells Activated by Avenin Peptides and Immuno-Dominant Hordein Peptides. J Autoimmun (2015) 56:56–65. 10.1016/j.jaut.2014.10.003 - DOI - PubMed
    1. Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, et al. . Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease. Sci Transl Med (2010) 2:41ra51. 10.1126/scitranslmed.3001012 - DOI - PubMed
    1. Christophersen A, Raki M, Bergseng E, Lundin KE, Jahnsen J, Sollid LM, et al. . Tetramer-Visualized Gluten-Specific CD4+ T Cells in Blood as a Potential Diagnostic Marker for Coeliac Disease Without Oral Gluten Challenge. United European Gastroenterol J (2014) 2:268–78. 10.1177/2050640614540154 - DOI - PMC - PubMed
    1. Sarna VK, Lundin KEA, Morkrid L, Qiao SW, Sollid LM, Christophersen A. HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption. Gastroenterology (2018) 154:886–96.e6. 10.1053/j.gastro.2017.11.006 - DOI - PubMed

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