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Case Reports
. 2021 Aug 19:16:86-89.
doi: 10.1016/j.jdcr.2021.08.007. eCollection 2021 Oct.

Dermatomyositis associated with hyponatremia and anasarca

Affiliations
Case Reports

Dermatomyositis associated with hyponatremia and anasarca

Madison Grinnell et al. JAAD Case Rep. .
No abstract available

Keywords: DM, dermatomyositis; NXP-2, nuclear matrix protein 2; anasarca; dermatomyositis; edema; hyponatremia.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Erythema overlying joints of hand, periungual area, and knees.
Fig 2
Fig 2
Computed tomography scans of abdomen/pelvis showing (A) diffuse subcutaneous anasarca with (B) notable mesenteric/retroperitoneal edema.
Fig 3
Fig 3
A, A skin biopsy of the upper portion of the left thigh demonstrating spongiosis with a mixed perivascular inflammatory infiltrate, focal interface dermatitis, and (B) diffusely positive MxA staining. (A, Hematoxylin-eosin stain; B, MxA stain; original magnifications: A, ×150; B, ×20.)
Fig 4
Fig 4
Diffusely positive interleukin 4 (A) and interleukin 31 (B) staining in the biopsy of the upper portion of the left thigh. (Original magnifications: A, ×20; B, ×20.)

References

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    1. Kumar A.H., Vikranth V. A rare case of dermatomyositis with hyponatremia. J Med Sci. 2015;1(3):58–59.
    1. Zeidi M., Chen K.L., Patel B., Ravishankar A., Lim R., Werth V.P. Increased MxA protein expression and dendritic cells in spongiotic dermatitis differentiates dermatomyositis from eczema in a single-center case-control study. J Cutan Pathol. 2021;48(3):364–373. - PMC - PubMed
    1. Jung K.D., Kim P.S., Park H.Y. Dermatomyositis associated with generalized subcutaneous edema and Evans syndrome. J Am Acad Dermatol. 2012;66(1):144–147. - PubMed
    1. Butt Z., Patel L., Das M.K., Mecoli C.A., Ramji A. NXP-2 positive dermatomyositis: a unique clinical presentation. Case Rep Rheumatol. 2017;2017:4817275. - PMC - PubMed

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