Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;125(2):145-150.
doi: 10.1002/jso.26675. Epub 2021 Sep 20.

The glottic-subglottic laryngectomy: Surgical technique, oncological, and functional outcomes

Affiliations

The glottic-subglottic laryngectomy: Surgical technique, oncological, and functional outcomes

Andy Bertolin et al. J Surg Oncol. 2022 Feb.

Abstract

Objectives: The aim of this article was to describe the surgical technique and report the oncological and functional outcomes of the partial glottic-subglottic laryngectomy (GSL).

Methods: A retrospective review of the clinical charts of patients who underwent GSL for laryngeal cancer from 1989 to 2020 at the Otolaryngology Unit of the Vittorio Veneto Hospital, a referral center for laryngeal cancer treatment.

Results: The present article considered 36 patients who were submitted to GSL for laryngeal cancer. The pathological exam found squamous cell carcinoma (SCC) in 16 cases, adenoid-cystic carcinoma (ACC) in 9 cases, laryngeal chondrosarcoma in 8 cases, 1 giant cell carcinoma, 1 carcinosarcoma, and 1 metastasis of colon adenocarcinoma. Considering the 16 SCC cases we observed a recurrence rate of 31%, the overall survival (OS) and disease-specific survival (DSS) were 75%. The 9 ACC cases had a recurrence rate of 23% and OS/DSS of 88%. In the 8 chondrosarcomas no relapses were reported and the OS/DSS were 100%. Among the patients without recurrence of the disease, a definitive decannulation was achieved in 21 cases (75%).

Conclusions: The GSL represents a valid alternative to total laryngectomy in selected cases of laryngeal cancer involving the glottic and subglottic regions.

Keywords: carcinoma; glottic; laryngeal; partial laryngectomy; subglottic.

PubMed Disclaimer

References

REFERENCES

    1. Succo G, Rizzotto G. Laringectomia glottico-ipoglottica: indicazioni e tecnica chirurgica. Relazione Ufficiale AOOI. 2010:439-454.
    1. Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA. Laryngeal adenoid cystic carcinoma: a systematic review. Otolaryngol Head Neck Surg. 2016;154(3):433-439. https://doi.org/10.1177/0194599815621884
    1. Lucioni M, Marioni G, Libera DD, et al. Treatment of unusual or rare laryngeal nonsquamous primary malignancies: radical (total/extended total laryngectomy) or conservative surgery? Am J Otolaryngol. 2008;29(2):106-112. https://doi.org/10.1016/j.amjoto.2007.02.007
    1. de Campora E, Radici M, de Campora L. Glottic-subglottic laryngectomy in the treatment of laryngeal tumors. Acta Otorhinolaryngol Ital. 2001;21(3):151-155.
    1. Serafini I. Laringectomia totale con mantenimento della respirazione per via naturale. Minerva Otorinolaring. 1970;17:119-126.

LinkOut - more resources