Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Apr 1;61(7):1055-1057.
doi: 10.2169/internalmedicine.7925-21. Epub 2021 Sep 18.

Cardiac Involvement of Adult T Cell Leukemia/Lymphoma

Affiliations
Case Reports

Cardiac Involvement of Adult T Cell Leukemia/Lymphoma

Makoto Yoshimitsu et al. Intern Med. .

Abstract

Adult T-cell leukemia/lymphoma (ATL) is a refractory T-cell lymphoma with variable clinical profiles, commonly exhibiting extra-nodal involvement. The myocardial involvement of ATL is often detected at an autopsy; however, the development of a symptomatic cardiac mass due to ATL is extremely rare. We herein report a 65-year-old man with ATL who developed cardiac symptoms due to a rapidly enlarging left ventricular mass soon after the initiation of systemic chemotherapy. We also summarize previously reported cases of symptomatic ATL with cardiac involvement.

Keywords: cardiac ATL; cardiac symptom.

PubMed Disclaimer

Conflict of interest statement

The authors state that they have no Conflict of Interest (COI).

Figures

Figure.
Figure.
A: Parasternal long-axis image obtained during the diagnosis of adult T-cell leukemia/lymphoma. B: Parasternal long-axis view obtained at the onset of cardiac symptoms.

References

    1. Sato E, Hasui K, Tokunaga M. Autopsy findings of adult T-cell lymphoma/leukemia. Gann Monogr Cancer Res 28: 51-64, 1982.
    1. Katsuya H, Ishitsuka K, Utsunomiya A, et al. Treatment and survival among 1594 patients with ATL. Blood 126: 2570-2577, 2015. - PubMed
    1. Suzumiya J, Marutsuka K, Nabeshima K, et al. Autopsy findings in 47 cases of adult T-cell leukemia/lymphoma in Miyazaki prefecture, Japan. Leuk Lymphoma 11: 281-286, 1993. - PubMed
    1. Ishida T, Jo T, Takemoto S, et al. Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: a randomized phase II study. Br J Haematol 169: 672-682, 2015. - PMC - PubMed
    1. Crump M, Baetz T, Couban S, et al. Gemcitabine, dexamethasone, and cisplatin in patients with recurrent or refractory aggressive histology B-cell non-Hodgkin lymphoma: a phase II study by the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG). Cancer 101: 1835-1842, 2004. - PubMed

Publication types