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Review
. 2021 Dec 1;27(6):642-648.
doi: 10.1097/MCC.0000000000000876.

Cardiac arrest in special circumstances

Affiliations
Review

Cardiac arrest in special circumstances

Carsten Lott et al. Curr Opin Crit Care. .

Abstract

Purpose of review: European Resuscitation Council Guidelines for Cardiopulmonary Resuscitation prioritize treatments like chest compression and defibrillation, known to be highly effective for cardiac arrest from cardiac origin. This review highlights the need to modify this approach in special circumstances.

Recent findings: Potentially reversible causes of cardiac arrest are clustered into four Hs and four Ts (Hypoxia, Hypovolaemia, Hyperkalaemia/other electrolyte disorders, Hypothermia, Thrombosis, Tamponade, Tension pneumothorax, Toxic agents). Point-of-care ultrasound has its role in identification of the cause and targeting treatment. Time-critical interventions may even prevent cardiac arrest if applied early. The extracorporeal CPR (eCPR) or mechanical CPR should be considered for bridging the period needed to reverse the precipitating cause(s). There is low quality of evidence available to guide the treatment in the majority of situations. Some topics (pulmonary embolism, eCPR, drowning, pregnancy and opioid toxicity) were included in recent ILCOR reviews and evidence updates but majority of recommendations is based on individual systematic reviews, scoping reviews, evidence updates and expert consensus.

Summary: Cardiac arrests from reversible causes happen with lower incidence. Return of spontaneous circulation and neurologically intact survival can hardly be achieved without a modified approach focusing on immediate treatment of the underlying cause(s) of cardiac arrest.

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References

    1. Soar J, Böttiger BW, Carli P, et al. European Resuscitation Council Guidelines 2021: adult advanced life support. Resuscitation 2021; 161:115–121.
    1. Safar P, Paradis NA, Weil MH. Paradis NA, Halperin HR, Kern KB, Wenzel V, Chamberlain DA. Asphyxial cardiac arrest. Cardiac arrest—the science and practice of resuscitation medicine. Cambridge: Cambridge University Press; 2007. 969–993.
    1. Kitamura T, Kiyohara K, Sakai T, et al. Epidemiology and outcome of adult out-of-hospital cardiac arrest of noncardiac origin in Osaka: a population-based study. BMJ Open 2014; 4:e006462.
    1. Ogawa T, Akahane M, Koike S, et al. Outcomes of chest compression only CPR versus conventional CPR conducted by lay people in patients with out of hospital cardiopulmonary arrest witnessed by bystanders: nationwide population based observational study. BMJ 2011; 342:c7106.
    1. Riva G, Ringh M, Jonsson M, et al. Survival in out-of-hospital cardiac arrest after standard cardiopulmonary resuscitation or chest compressions only before arrival of emergency medical services: nationwide study during three guideline periods. Circulation 2019; 139:2600–2609.