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. 2022 Jan;36(1):e20-e22.
doi: 10.1111/jdv.17680. Epub 2021 Sep 30.

SARS-CoV-2 mRNA vaccine injection site pseudolymphoma

D Mintoff  1   2 , L Scerri  1 , A Betts  3
Affiliations

SARS-CoV-2 mRNA vaccine injection site pseudolymphoma

D Mintoff et al. J Eur Acad Dermatol Venereol. 2022 Jan.
No abstract available

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Conflict of interest statement

None of the authors have any relevant conflicts or funding to disclose.

Figures

Figure 1
Figure 1
(a) Erythematous nodule on the patient’s left arm as observed clinically. (b) Dermoscopic evaluation of the nodule revealed dotted vessels on an erythematous background and shiny white lines.
Figure 2
Figure 2
(a) Nodular lymphoid infiltrate extending from the superficial dermis to the deep dermis, with a focal interface at the basal layers of the epidermis. (H&E, x100). (b) Polymorphous infiltrate with a predominance of small mature lymphocytes. (H&E, x 200). Immunohistochemistry shows a mixture of B and T cells, highlighted by CD3 (c) and CD20 (d) respectively, with a predominance of T cells (x100).
See this image and copyright information in PMC

References

    1. Maubec E, Pinquier L, Viguier M et al. Vaccination‐induced cutaneous pseudolymphoma. J Am Acad Dermatol 2005; 52: 623–629. - PubMed
    1. Baden LR, El Sahly HM, Essink B et al. Efficacy and safety of the mRNA‐1273 SARS‐CoV‐2 vaccine. N Engl J Med 2021; 384: 403–416. - PMC - PubMed
    1. Ramos Pinheiro R, Duarte B, João A, Lencastre A. Cutaneous pseudolymphoma following quadrivalent human papillomavirus vaccination ‐ a rare adverse event. J Dtsch Dermatol Ges 2018; 16: 465–467. - PubMed
    1. Cerroni L, Borroni RG, Massone C, Chott A, Kerl H. Cutaneous B‐cell pseudolymphoma at the site of vaccination. Am J Dermatopathol 2007; 29: 538–542. - PubMed
    1. Pfizer, Inc . Vaccine information fact sheet for recipients and caregivers about comirnaty (COVID‐19 vaccine, mRNA) and Pfizer‐BioNTech COVID‐19 vaccine to prevent coronavirus disease 2019 (COVID‐19). 2021. https://www.fda.gov/media/144414/download.