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. 2021 Sep 20;7(3):00407-2021.
doi: 10.1183/23120541.00407-2021. eCollection 2021 Jul.

Effective treatment of late-onset noninfectious pulmonary complication with ruxolitinib in an 8-year-old boy

Maria Di Cicco  1 , Ester Del Tufo  1 , Eva Parolo  1 , Mariacristina Menconi  2 , Sayla Bernasconi  2 , Chiara Romei  3 , Alessandro Di Gangi  1 , Beatrice Masini  1 , Diego Peroni  1 , Gabriella Casazza  2
Affiliations

Effective treatment of late-onset noninfectious pulmonary complication with ruxolitinib in an 8-year-old boy

Maria Di Cicco et al. ERJ Open Res. .

Abstract

Ruxolitinib could be considered as an option in the treatment of LONIPCs in children when other treatments are ineffective. Spirometry is a valuable tool for both diagnosis and follow-up of LONIPCs in children. https://bit.ly/3BmOYfb.

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Conflict of interest statement

Conflict of interest: The authors have no conflicts of interest relevant to this article to disclose.

Figures

FIGURE 1
FIGURE 1
Lung function testing trend by means of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) values.
See this image and copyright information in PMC

References

    1. Patriarca F, Skert C, Sperotto A, et al. . Incidence, outcome, and risk factors of late-onset noninfectious pulmonary complications after unrelated donor stem cell transplantation. Bone Marrow Transplant 2004; 33: 751–758. doi:10.1038/sj.bmt.1704426 - DOI - PubMed
    1. Carreras E, Cooke KR. Noninfectious pulmonary complications. In:Carreras E, Dufour C, Mohty M, et al., eds. The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies. 7th Edn. Cham, Springer, 2019; pp. 393–407. - PubMed
    1. Palmas A, Tefferi A, Myers JL, et al. . Late-onset noninfectious pulmonary complications after allogeneic bone marrow transplantation. Br J Haematol 1998; 100: 680–687. doi:10.1046/j.1365-2141.1998.00617.x - DOI - PubMed
    1. Hildebrandt GC, Fazekas T, Lawitschka A, et al. . Diagnosis and treatment of pulmonary chronic GVHD: report from the consensus conference on clinical practice in chronic GVHD. Bone Marrow Transplant 2011; 46: 1283–1295. doi:10.1038/bmt.2011.35 - DOI - PMC - PubMed
    1. Bergeron A, Chevret S, Peffault de Latour R, et al. . Noninfectious lung complications after allogeneic haematopoietic stem cell transplantation. Eur Respir J 2018; 51: 1702617. doi:10.1183/13993003.02617-2017 - DOI - PubMed

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