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. 2022 Jan 18;34(2):283-290.
doi: 10.1093/icvts/ivab256.

Total arch replacement in octogenarians

Kohei Hachiro  1 , Takeshi Kinoshita  1 , Tomoaki Suzuki  1 , Tohru Asai  1
Affiliations

Total arch replacement in octogenarians

Kohei Hachiro et al. Interact Cardiovasc Thorac Surg. .

Abstract

Objectives: We investigated the effect of a preoperative age ≥80 years on postoperative outcomes in patients who underwent isolated elective total arch replacement using mild hypothermic lower body circulatory arrest with bilateral antegrade selective cerebral perfusion.

Methods: A total of 140 patients who had undergone isolated elective total arch replacement between January 2007 and December 2020 were enrolled in the present study. We compared postoperative outcomes between 30 octogenarian patients (≥80 years old; Octogenarian group) and 110 non-octogenarian patients (≤79 years old; Non-Octogenarian group).

Results: Overall 30-day mortality and hospital mortality were 0% in both groups, and there was no significant difference in overall survival between the 2 groups (log-rank test, P = 0.108). Univariable Cox proportional hazard analysis showed that age as continuous variable was only the predictor of mid-term all-cause death (hazard ratio 1.08, 95% confidence interval 1.01-1.16; P = 0.037), but not in the Octogenarians subgroup (P = 0.119).

Conclusions: Preoperative age ≥80 years is not associated with worse outcomes postoperatively after isolated elective total arch replacement with mild hypothermic lower body circulatory arrest and bilateral antegrade selective cerebral perfusion.

Keywords: Octogenarians; Total arch replacement.

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Figures

Figure 1:
Figure 1:
Number of total arch replacement operations in our institution.
Figure 2:
Figure 2:
Patient population in this study.
Figure 3:
Figure 3:
Distance between the skin and distal anastomosis.
Figure 4:
Figure 4:
Freedom from overall death.
None
See this image and copyright information in PMC

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