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Review
. 2021 Jul 5;19(3):340-345.
doi: 10.1080/2090598X.2021.1948158. eCollection 2021.

Low-intensity extracorporeal shockwave therapy for erectile dysfunction

Onder Canguven  1 , Kareim Khalafalla  1 , Abdulla Al Ansari  1
Affiliations
Review

Low-intensity extracorporeal shockwave therapy for erectile dysfunction

Onder Canguven et al. Arab J Urol. .

Abstract

Objectives: To review the current evidence of clinical effectiveness of low-intensity extracorporeal shockwave therapy (LI-ESWT) treatment for erectile dysfunction (ED).

Methods: A selective database search using Medical Subject Headings (MeSH) terms 'low intensity extracorporeal shock wave therapy' and 'erectile dysfunction' was conducted in accordance with the Preferred Reporting Items for Systemic Reviews and Meta Analyses (PRISMA) guidelines to review the effectiveness of LI-ESWT for ED. We performed a systematic search of publications using the PubMed and Web of Science databases (January 2010-December 2020) for prospective randomised clinical trials (RCTs). The success rate of LI-ESWT associated with ED were recorded and analysed.

Results: A total of 106 articles were reviewed after searching for the keywords. Overall, 11 RCTs were included in this systematic review. A total of 920 male patients were treated in 11 RCTs. The patients' ages ranged from 18 to 80 years and they had ≥3 months of ED symptoms. Vasculogenic and neurogenic causes were addressed in 81% and 19% of patients, respectively. Of the 920 patients, 348 patients had a statistically significant improvement in their erectile function after LI-ESWT; however, 572 did not have a statistically significant improvement.

Conclusions: The present review found that LI-ESWT has a role in ED treatment in laboratory studies, but its role in human clinical trials is still controversial. Further good quality studies need to be conducted to properly assess its true potential in ED treatment.

Keywords: Low-intensity extracorporeal shockwave therapy; erectile dysfunction; erection; male.

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Conflict of interest statement

No potential conflict of interest was reported by the authors.

Figures

Figure 1.
Figure 1.
Study flowchart
See this image and copyright information in PMC

References

    1. Al Naimi A, Majzoub AA, Talib RA, et al. Erectile dysfunction in qatar: prevalence and risk factors in 1,052 participants-a pilot study. Sex Med. 2014;2:91–95. - PMC - PubMed
    1. Burnett AL, Nehra A, Breau RH, et al. Erectile Dysfunction: AUA Guideline. J Urol. 2018;200:633–641. - PubMed
    1. Salter CA, Lue TF, Mulhall JP.. What is shockwave therapy? J Sex Med. 2020;17:565–569. - PubMed
    1. Medispec Ltd . The omnispec extracorporeal shock wave therapy system. [cited Apr 2021]. Available from: http://us.medispec.com/about-us/products/urology/ed1000/
    1. Medispec Ltd . ED1000™. EDSWT™. Erectile dysfunction shock wave therapy. New hope for men who suffer from ED. Available from: http://www.medispec.com/wp-content/uploads/2019/05/ED1000-Brochure-OR-5-...

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