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. 2022 Jun;27(5):1679-1686.
doi: 10.1007/s40519-021-01304-3. Epub 2021 Sep 23.

Changes in appetite, taste, smell, and food aversion in post-bariatric patients and their relations with surgery time, weight loss and regain

Karynne Grutter Lopes  1 , Gabriel Pires Dos Santos  2 , Eline Coan Romagna  1 , Diogo Menezes Ferrazani Mattos  3 , Tassia Gomide Braga  1 , Carolina Bastos Cunha  1 , Priscila Alves Maranhão  4 , Luiz Guilherme Kraemer-Aguiar  5   6
Affiliations

Changes in appetite, taste, smell, and food aversion in post-bariatric patients and their relations with surgery time, weight loss and regain

Karynne Grutter Lopes et al. Eat Weight Disord. 2022 Jun.

Abstract

Purpose: We aimed to study the occurrence of long-term changes in appetite, taste, smell perceptions, and food aversion in patients following bariatric surgery. Additionally, we compared two surgery types, excess weight loss, rate of weight regain, and time since surgery.

Methods: This cross-sectional study included 146 post-bariatric patients who were without regular medical follow-up (126 post-Roux-en-Y gastric bypass [RYGB] and 20 post-sleeve gastrectomy [SG]), aged 42 ± 8 years, BMI of 32.6 ± 6.3 kg/m2, with excess weight loss of 87.5 ± 20.2%, rate of weight regain (RWR) of 15.4 [3.9-30.9]% and time since surgery of 5.0 ± 4.0 years. They answered a questionnaire about sensory and food perceptions at their first medical appointment at our unit.

Results: Changes in appetite (76%), taste (48.6%), and an increased sensation for sweet taste (60.2%) frequently occurred in our sample. Sensory and food aversion perceptions, taste changes to specific foods, and loss level of taste and smell were similar between RYGB and SG. No differences between patients with or without changes in appetite, taste, smell, and food aversion perceptions concerning excess weight loss were observed. The RWR in post-RYGB was lower in those with changes in taste and smell (P = 0.05). Sensory changes were noted in those with shorter time since surgery for both surgeries (P ≤ 0.05).

Conclusion: Changes in appetite and taste occurred frequently in our patients even in the long term. Post-RYGB patients with lower RWR had more changes in taste and smell while a shorter time since surgery showed more frequent changes in appetite, taste, and smell.

Level of evidence: Level V, cross-sectional study.

Trial registration number: ClinicalTrials.gov (NCT04193384).

Keywords: Appetite; Bariatric surgery; Food aversion; Smell; Taste.

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References

    1. Reges O, Greenland P, Dicker D, Leibowitz M, Hoshen M, Gofer I, Rasmussen-Torvik LJ, Balicer RD (2018) Association of bariatric surgery using laparoscopic banding, Roux-en-Y gastric bypass, or laparoscopic sleeve gastrectomy vs usual care obesity management with all-cause mortality. JAMA 319(3):279–290. https://doi.org/10.1001/jama.2017.20513 - DOI - PubMed - PMC
    1. Sjöström CD, Lissner L, Wedel H, Sjöström L (1999) Reduction in incidence of diabetes, hypertension and lipid disturbances after intentional weight loss induced by bariatric surgery: the SOS Intervention Study. Obes Res 7(5):477–484. https://doi.org/10.1002/j.1550-8528.1999.tb00436.x - DOI - PubMed
    1. Sweeney TE, Morton JM (2014) Metabolic surgery: Action via hormonal milieu changes, changes in bile acids or gut microbiota? A summary of the literature. Best Pract Res Clin Gastroenterol 28(4):727–740. https://doi.org/10.1016/j.bpg.2014.07.016 - DOI - PubMed - PMC
    1. Dimitriadis GK, Randeva MS, Miras AD (2017) Potential hormone mechanisms of bariatric surgery. Curr Obes Rep 6(3):253–265. https://doi.org/10.1007/s13679-017-0276-5 - DOI - PubMed - PMC
    1. Behary P, Miras AD (2015) Food preferences and underlying mechanisms after bariatric surgery. Proce Nutr Soc 74(4):419–425. https://doi.org/10.1017/S0029665115002074 - DOI

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