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Review
. 2021 Sep 23;15(9):e0009717.
doi: 10.1371/journal.pntd.0009717. eCollection 2021 Sep.

Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies

Carolina Rosadas  1 , Maria Luiza B Menezes  2 , Bernardo Galvão-Castro  3 , Tatiane Assone  4 , Angélica E Miranda  5 , Mayra G Aragón  5 , Adele Caterino-de-Araujo  6 , Graham P Taylor  1 , Ricardo Ishak  7
Affiliations
Review

Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies

Carolina Rosadas et al. PLoS Negl Trop Dis. .

Abstract

Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but remain silent and neglected infections. HTLV-1 is associated with a range of diseases with high morbidity and mortality. There is no curative treatment for this lifelong infection, so measures to prevent transmission are essential. This narrative review discusses HTLV-1/2 transmission routes and measures to prevent its continuous dissemination. The public health policies that are currently implemented in Brazil to avoid HTLV-1/2 transmission are addressed, and further strategies are proposed.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flowchart proposal for management of HTLV-1/2 infection in pregnant women and prevention of mother-to-child transmission.
CMIA, chemiluminescence assay; HTLV-1/2, human T-cell lymphotropic virus 1 and 2; LIA, line immunoassay; WB, western blot.
See this image and copyright information in PMC

References

    1. Gessain A, Cassar O. Epidemiological Aspects and World Distribution of HTLV-1 Infection. Front Microbiol. 2012;3:388. doi: 10.3389/fmicb.2012.00388 - DOI - PMC - PubMed
    1. CGIST/DDCI/SVS C-G de V das IST, Rosadas C, Espinosa Miranda A, Utscg Gonçalves D, Caterino-de-Araujo A, Assone T, et al. Prevalência da Infecção por HTLV-1/2 no Brasil. Bol Epidemiológico. 2020;51. Available: https://www.gov.br/saude/pt-br/media/pdf/2020/dezembro/11/boletim_epidem...
    1. Rosadas C, Assone T, Yamashita M, Adonis A, Puccioni-Sohler M, Santos M, et al. Health state utility values in people living with htlv-1 and in patients with ham/tsp: The impact of a neglected disease on the quality of life. PLoS Negl Trop Dis. 2020;14. doi: 10.1371/journal.pntd.0008761 - DOI - PMC - PubMed
    1. Andrade R, Tanajura D, Santana D, dos Santos D, Carvalho EM. Association between urinary symptoms and quality of life in HTLV-1 infected subjects without myelopathy. Int Braz J Urol. 2013;39:861–6. doi: 10.1590/S1677-5538.IBJU.2013.06.13 - DOI - PubMed
    1. Gascón MRP, Capitão CG, Casseb J, Nogueira-Martins MCF, Smid J, Oliveira ACP. de. Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients. Braz J Infect Dis. 15: 578–82. Available. http://www.ncbi.nlm.nih.gov/pubmed/22218518. doi: 10.1590/s1413-86702011000600013 - DOI - PubMed

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