Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Sep 23;76(Suppl 3):iii4-iii11.
doi: 10.1093/jac/dkab245.

Syndromic diagnostic testing: a new way to approach patient care in the treatment of infectious diseases

Lisa E Dumkow  1 , Lacy J Worden  1 , Sonia N Rao  2
Affiliations
Review

Syndromic diagnostic testing: a new way to approach patient care in the treatment of infectious diseases

Lisa E Dumkow et al. J Antimicrob Chemother. .

Abstract

Advanced microbiology technologies such as multiplex molecular assays (i.e. syndromic diagnostic tests) are a novel approach to the rapid diagnosis of common infectious diseases. As the global burden of antimicrobial resistance continues to rise, the judicious use of antimicrobials is of utmost importance. Syndromic panels are now being recognized in some clinical practice guidelines as a 'game-changer' in the diagnosis of infectious diseases. These syndromic panels, if implemented thoughtfully and interpreted carefully, have the potential to improve patient outcomes through improved clinical decision making, optimized laboratory workflow, and enhanced antimicrobial stewardship. This paper reviews the potential benefits of and considerations regarding various infectious diseases syndromic panels, and highlights how to maximize impact through collaboration between clinical microbiology laboratory and antimicrobial stewardship programmes.

PubMed Disclaimer

References

    1. Centers for Disease Control and Prevention. Core Elements of Hospital Antibiotic Stewardship Programs. https://www.cdc.gov/antibiotic-use/core-elements/hospital.html.
    1. Hay SI, Rao PC, Dolecek C. et al.Measuring and mapping the global burden of antimicrobial resistance. BMC Med 2018; 16: 78. - PMC - PubMed
    1. Theuretzbacher U, Bush K, Harbarth S. et al.Critical analysis of antibacterial agents in clinical development. Nat Rev Microbiol 2020; 18: 286–98. - PubMed
    1. Buchan BW, Ledeboer NA.. Emerging technologies for the clinical microbiology laboratory. Clin Microbiol Rev 2014; 27: 783–822. - PMC - PubMed
    1. Graf EH, Pancholi P.. Appropriate use and future directions of molecular diagnostic testing. Curr Infect Dis Rep 2020; 22: 5. - PMC - PubMed

Publication types

Substances