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. 2021 Sep;26(38):2100833.
doi: 10.2807/1560-7917.ES.2021.26.38.2100833.

mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021

Baltazar Nunes  1   2 , Ana Paula Rodrigues  1 , Irina Kislaya  1   2 , Camila Cruz  3 , André Peralta-Santos  4 , João Lima  3 , Pedro Pinto Leite  4 , Duarte Sequeira  3 , Carlos Matias Dias  1   2 , Ausenda Machado  1   2
Affiliations

mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021

Baltazar Nunes et al. Euro Surveill. 2021 Sep.

Abstract

Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88-97) and 82% (95% CI: 72-89) for those 65-79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92-98) and 81% (95% CI: 74-87) in these two age groups.

Keywords: COVID-19 related death; SARS-CoV-2; Vaccine Effectiveness; hospitalisation; older adults.

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Conflict of interest statement

Conflict of interest: None declared.

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