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. 2022 Jun 1;106(6):1201-1205.
doi: 10.1097/TP.0000000000003958. Epub 2022 Sep 23.

Healthcare Resource Utilization After Living Liver Donation: A Retrospective Case-Control Study

Hyunjae Im  1   2 , Eun Jin Jang  3 , Junwoo Jo  4 , Suk Hyung Choe  1 , Somin Joo  1 , Hannah Lee  1 , Seung-Young Oh  2   5 , Suk Kyun Hong  5 , Ho Geol Ryu  1   2
Affiliations

Healthcare Resource Utilization After Living Liver Donation: A Retrospective Case-Control Study

Hyunjae Im et al. Transplantation. .

Abstract

Background: Living liver donation is generally considered safe, but donors may experience short- or long-term complications. The purpose of this study was to assess healthcare resource utilization after liver donation in living liver donors in comparison with the general population.

Methods: Outpatient or emergency department visits and hospital admissions were compared between living liver donors who underwent hepatic resection for living liver donation between 2004 and 2018 and the matched general population. Healthcare resource utilization data for 5 y after liver donation were collected from the National Health Insurance Service database. For every living liver donor, 4 individually matched nondonors were selected from the National Health Insurance Service database using age, sex, preexisting comorbidities, and previous healthcare utilization history.

Results: A total of 1886 living liver donors and 7309 nondonors were included. In the first year after donation, living liver donors required more outpatient department visits (7 [4-13] versus 3 [1-7], P < 0.001) and more emergency department visits (13.33% versus 0.15%, P < 0.001) compared with matched nondonors. A similar trend persisted for 5 y after donation. The number of hospital admissions of living liver donors was higher for up to 2 y after donation with longer hospital length of stay (13.0 [10.5-16.0] d versus 5.0 [3.0-9.0] d, P < 0.0001).

Conclusions: Healthcare resource utilization in living liver donors for 5 y after donation was higher compared with matched nondonors. The higher healthcare resource demand may be related to postoperative complications or lowered threshold for healthcare resource utilization after donation.

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Conflict of interest statement

The authors declare no conflicts of interest.

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References

    1. Murray KF, Carithers RL Jr. AASLD practice guidelines: evaluation of the patient for liver transplantation. Hepatology. 2005;41:1407–1432.
    1. Ahmed A, Keeffe EB. Current indications and contraindications for liver transplantation. Clin Liver Dis. 2007;11:227–247.
    1. Kwong AJ, Lai JC, Dodge JL, et al. Outcomes for liver transplant candidates listed with low model for end-stage liver disease score. Liver Transpl. 2015;21:1403–1409.
    1. Abu-Gazala S, Olthoff KM. Current status of living donor liver transplantation in the United States. Annu Rev Med. 2019;70:225–238.
    1. Spital A. Ethical issues in living organ donation: donor autonomy and beyond. Am J Kidney Dis. 2001;38:189–195.

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