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Review
. 2021;21(23):2101-2108.
doi: 10.2174/1568026621666210924160004.

Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa

Mohammad Anwar Hossain  1 , Nadezhda A German  2
Affiliations
Review

Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa

Mohammad Anwar Hossain et al. Curr Top Med Chem. 2021.

Abstract

Modulators of quorum sensing pathways in Pseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti-virulence agents capable of increasing the existing therapeutic agents' efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.

Keywords: Pseudomonas aeruginosa; quorum sensing; quorum sensing inhibitors.; virulence factors.

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