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. 2022 Jul;279(7):3415-3423.
doi: 10.1007/s00405-021-07094-9. Epub 2021 Sep 25.

Evaluation of retrootolithic function using galvanic vestibular-evoked myogenic potentials in patients with benign paroxysmal positional vertigo

Chih-Ming Chang  1   2   3 , Wu-Chia Lo  2   3   4 , Yi-Ho Young  3 , Li-Jen Liao  2   3   5   6 , Po-Hsuan Wu  2   7 , Ping-Chia Cheng  2 , Po-Wen Cheng  8   9
Affiliations

Evaluation of retrootolithic function using galvanic vestibular-evoked myogenic potentials in patients with benign paroxysmal positional vertigo

Chih-Ming Chang et al. Eur Arch Otorhinolaryngol. 2022 Jul.

Abstract

Purpose: The purpose is to investigate possible vestibulopathy in patients with benign paroxysmal positional vertigo (BPPV), inner ear tests, including cervical and ocular vestibular-evoked myogenic potentials (cVEMPs and oVEMPs) via various stimulation modes, were adopted.

Methods: Fifty BPPV patients were enrolled in this study. All patients underwent pure tone audiometry, cVEMPs, oVEMPs, and caloric tests. The recurrence status, abnormal rates of inner ear tests, and the characteristic parameters of VEMPs, such as wave latencies and amplitudes, were analyzed.

Results: In affected ears, the abnormal rates of acoustic cVEMPs, vibratory oVEMPs, galvanic cVEMPs, and galvanic oVEMPs were 62%, 28%, 36%, and 14%, respectively. The abnormalities of acoustic cVEMPs were significantly larger than those of vibratory oVEMPs, and acoustic/vibratory VEMPs had significantly higher abnormal rates than the corresponding galvanic VEMPs.

Conclusion: BPPV patients may have both otolithic and neural dysfunctions. Otolithic organ damage occurs more frequently than retrootolithic neural degeneration, and the saccular macula might have a greater extent of damage than the utricular macula.

Keywords: Benign paroxysmal positional vertigo; Cervical vestibular-evoked myogenic potential; Galvanic vestibular stimulation; Ocular vestibular-evoked myogenic potential.

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References

    1. von Brevern M, Radtke A, Lezius F, Feldmann M, Ziese T, Lempert T, Neuhauser H (2007) Epidemiology of benign paroxysmal positional vertigo: a population based study. J Neurol Neurosurg Psychiatry 78:710–715. https://doi.org/10.1136/jnnp.2006.100420 - DOI
    1. Schuknecht HF (1969) Cupulolithiasis. Arch Otolaryngol 90:765–778. https://doi.org/10.1001/archotol.1969.00770030767020 - DOI - PubMed
    1. Walther LE, Wenzel A, Buder J, Bloching MB, Kniep R, Blödow A (2014) Detection of human utricular otoconia degeneration in vital specimen and implications for benign paroxysmal positional vertigo. Eur Arch Otorhinolaryngol 271:3133–3138. https://doi.org/10.1007/s00405-013-2784-6 - DOI - PubMed
    1. Kao WT, Parnes LS, Chole RA (2017) Otoconia and otolithic membrane fragments within the posterior semicircular canal in benign paroxysmal positional vertigo. Laryngoscope 127:709–714. https://doi.org/10.1002/lary.26115 - DOI - PubMed
    1. Korres S, Gkoritsa E, Giannakakou-Razelou D, Yiotakis I, Riga M, Nikolpoulos TP (2011) Vestibular evoked myogenic potentials in patients with BPPV. Med Sci Monit 17:CR42-47. https://doi.org/10.12659/msm.881328 - DOI - PubMed - PMC

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