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Review
. 2021 Sep 1;8(3):418-425.
doi: 10.3390/dermatopathology8030044.

Artificial Intelligence in Dermatopathology: New Insights and Perspectives

Gerardo Cazzato  1 , Anna Colagrande  1 , Antonietta Cimmino  1 , Francesca Arezzo  2 , Vera Loizzi  2 , Concetta Caporusso  1 , Marco Marangio  3 , Caterina Foti  4 , Paolo Romita  4 , Lucia Lospalluti  4 , Francesco Mazzotta  5 , Sebastiano Cicco  6 , Gennaro Cormio  2 , Teresa Lettini  1 , Leonardo Resta  1 , Angelo Vacca  6 , Giuseppe Ingravallo  1
Affiliations
Review

Artificial Intelligence in Dermatopathology: New Insights and Perspectives

Gerardo Cazzato et al. Dermatopathology (Basel). .

Abstract

In recent years, an increasing enthusiasm has been observed towards artificial intelligence and machine learning, involving different areas of medicine. Among these, although still in the embryonic stage, the dermatopathological field has also been partially involved, with the attempt to develop and train algorithms that could assist the pathologist in the differential diagnosis of complex melanocytic lesions. In this article, we face this new challenge of the modern era, carry out a review of the literature regarding the state of the art and try to determine promising future perspectives.

Keywords: AI; dermatopathology; future; machine learning; skin.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Literature search and article selection.
Figure 2
Figure 2
Examples of images of lesions used in various studies in the literature. (A) Basal cell carcinoma, superficial variant (hematoxylin–eosin, original magnification: 4×). (B) Seborrheic keratosis, hyperkeratotic variant (hematoxylin–eosin, original magnification: 10×). (C) Squamous cell carcinoma (hematoxylin–eosin, original magnification: 20×). (D) Intradermic nevus (hematoxylin–eosin, original magnification: 10×). (E) Amelanotic malignant melanoma (hematoxylin–eosin, original magnification: 20×).
Figure 2
Figure 2
Examples of images of lesions used in various studies in the literature. (A) Basal cell carcinoma, superficial variant (hematoxylin–eosin, original magnification: 4×). (B) Seborrheic keratosis, hyperkeratotic variant (hematoxylin–eosin, original magnification: 10×). (C) Squamous cell carcinoma (hematoxylin–eosin, original magnification: 20×). (D) Intradermic nevus (hematoxylin–eosin, original magnification: 10×). (E) Amelanotic malignant melanoma (hematoxylin–eosin, original magnification: 20×).
See this image and copyright information in PMC

References

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