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. 2021;6(12):1075-1076.
doi: 10.1038/s41578-021-00379-9. Epub 2021 Sep 21.

From lipids to lipid nanoparticles to mRNA vaccines

Christine Horejs  1
Affiliations

From lipids to lipid nanoparticles to mRNA vaccines

Christine Horejs. Nat Rev Mater. 2021.

Abstract

Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of lipid nanoparticle-nucleic acid drugs.

Keywords: Drug delivery; Lipids; Nanoparticles; Nucleic-acid therapeutics; RNA.

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