Editorial: Development and Applications of New Activity-Based Probes

Galia Blum^{1

2}, Steven H L Verhelst^{3

4}, Xiaowei Ma⁵

Affiliations

¹ The Faculty of Medicine, The School of Pharmacy, The Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.
² The Wohl Institute for Translational Medicine, The Goldyne Savad Institute for Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
³ KU Leuven, Department of Cellular and Molecular Medicine, Leuven, Belgium.
⁴ Leibniz Institute for Analytical Sciences ISAS, Dortmund, Germany.
⁵ Department of Nuclear Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.

Editorial

Galia Blum et al. Front Chem. 2021.

. 2021 Sep 9:9:754294.

doi: 10.3389/fchem.2021.754294. eCollection 2021.

Galia Blum^{1

2}, Steven H L Verhelst^{3

4}, Xiaowei Ma⁵

¹ The Faculty of Medicine, The School of Pharmacy, The Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.
² The Wohl Institute for Translational Medicine, The Goldyne Savad Institute for Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
³ KU Leuven, Department of Cellular and Molecular Medicine, Leuven, Belgium.
⁴ Leibniz Institute for Analytical Sciences ISAS, Dortmund, Germany.
⁵ Department of Nuclear Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.

No abstract available

Keywords: ABP application; ABP generation; activity-based probe; protease probes; recognition element.

Conflict of interest statement

The authors declare no commercial or financial relationship that could be construed as a potential conflict of interest.

Editorial on the Research TopicDevelopment and Applications of New Activity-Based Probes

1. Chen S., Lovell S., Lee S., Fellner M., Mace P. D., Bogyo M. (2021). Identification of Highly Selective Covalent Inhibitors by Phage Display. Nat. Biotechnol. 39 (4), 490–498. 10.1038/s41587-020-0733-7 - DOI - PMC - PubMed
1. Poreba M., Kasperkiewicz P., Snipas S. J., Fasci D., Salvesen G. S., Drag M. (2014). Unnatural Amino Acids Increase Sensitivity and Provide for the Design of Highly Selective Caspase Substrates. Cell Death Differ 21 (9), 1482–1492. 10.1038/cdd.2014.64 - DOI - PMC - PubMed