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. 2021 Oct;69(10):2650-2656.
doi: 10.4103/ijo.IJO_3365_20.

Short term changes in corneal stress-strain index and other corneal biomechanical parameters post-laser in situ keratomileusis

Vaishal P Kenia  1 , Raj V Kenia  2 , Onkar H Pirdankar  3
Affiliations

Short term changes in corneal stress-strain index and other corneal biomechanical parameters post-laser in situ keratomileusis

Vaishal P Kenia et al. Indian J Ophthalmol. 2021 Oct.

Abstract

Purpose: To report the short-term changes in a corneal stress-strain index (SSI) and other corneal biomechanical parameters post-laser in situ keratomileusis (LASIK) surgery.

Methods: A retrospective study was conducted at a tertiary eye care center wherein patients who had undergone LASIK (microkeratome blade and femtosecond bladeless LASIK) between July and December 2019 were enrolled. Patients of age group 20-40 years, best-corrected visual acuity of 20/20, intraocular pressure (IOP) <22 mmHg, pre-LASIK pachymetry >500 microns, and corneal astigmatism ≤3.00 D were included. Subjects with a prior history of refractive surgery, any other ocular or systemic disease, poor-quality scans, intraoperative complications, and missing data were excluded. Corneal biomechanical properties including SSI were analyzed using Corvis ST and compared using the Paired T-test for each group separately at pre-LASIK, and 1-month post-operatively.

Results: Overall, 202 eyes were reviewed, and 79 eyes fulfilled the inclusion criteria. Forty-three and 36 eyes had undergone Microkeratome Blade LASIK (Group I) and Femto LASIK (Group II), respectively. Overall, 29 and 26 corneal biomechanical parameters out of 33 changed significantly post-Microkeratome Blade LASIK and Femto LASIK, respectively. Statistically significant changes were noted in all the parameters at A1, maximum and Vinciguerra screening parameters (P < 0.001), however, no changes were noted in SSI in both the groups when compared with the pre-surgery data.

Conclusion: Though the reduction in SSI was not statistically significant, other biomechanical parameters showed significant biomechanical changes pre- and post-LASIK surgeries in both the groups. However, a long-term study with a larger sample size would be required to understand the changes and stability in SSI post-refractive surgery.

Keywords: Corneal biomechanics; Corneal stress-strain index (SSI); LASIK.

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Conflict of interest statement

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