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. 2021 Aug 29;11(9):1568.
doi: 10.3390/diagnostics11091568.

Spontaneous Upper Urinary Tract Rupture Caused by Ureteric Stones: Clinical Characteristics and Validation of a Radiological Classification System

Carolina Bebi  1 , Matteo Giulio Spinelli  1 , Gianpaolo Lucignani  1 , Pierpaolo Biondetti  2 , Laura Martinetti  2 , Irene Fulgheri  2 , Elisa De Lorenzis  1   3 , Giancarlo Albo  1   3 , Annamaria Ierardi  2 , Franco Palmisano  1 , Andrea Salonia  4 , Gianpaolo Carrafiello  2 , Emanuele Montanari  1   3 , Luca Boeri  1
Affiliations

Spontaneous Upper Urinary Tract Rupture Caused by Ureteric Stones: Clinical Characteristics and Validation of a Radiological Classification System

Carolina Bebi et al. Diagnostics (Basel). .

Abstract

Background: This study seeks to validate a radiological classification system of spontaneous upper urinary tract rupture (sUUTR) and to analyse its relationship with clinical, laboratory and radiological characteristics of sUUTR.

Methods: We analysed data from 66 patients with a computerised tomography (CT)-proven sUUTR treated with ureteral or nephrostomy catheter positioning. Comorbidities were scored with the Charlson Comorbidity Index (CCI). All CT scans were reviewed by two experienced radiologists and one urologist, who classified sUUTR in (a) local spread, (b) free fluid and (c) urinoma. Interobserver agreement for radiological score was evaluated with the Intraclass Correlation Coefficient (ICC) and Cohen's Kappa analyses. Descriptive statistics and logistic regression models verified the association between clinical variables and sUUTR severity.

Results: The interobserver agreement for sUUTR classification was high among radiologists and between the radiologists and the urologist (all Kappa > 0.7), with an overall high interrater reliability (ICC 0.82). Local spread, free fluid and urinoma were found in 24 (36.4%), 39 (59.1%) and 3 (4.5%) cases, respectively. Patients with free fluid/urinoma had higher rate of CCI ≥ 1 than those with local spread (40.5% vs. 16.7%, p = 0.04). Intraoperative absence of urine extravasation was more frequently found in patients with local spread than those with free fluid/urinoma (66.7% vs. 28.6%, p < 0.01). Multivariable logistic regression analysis revealed that local spread (OR 4.5, p < 0.01) was associated with absence of contrast medium extravasation during pyelography, after accounting for stone size, fever and CCI.

Conclusions: The analysed sUUTR classification score had good inter/intra-reader reliability among radiologists and urologists. Absence of urine extravasation was five times more frequent in patients with local spread, making conservative treatment feasible in these cases.

Keywords: classification system; emergency; radiology; spontaneous upper urinary tract rupture; ureteric stones.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Axial computerised tomography characteristics of local spread at delayed excretory phase. Arrows indicate the leakage point.
Figure 2
Figure 2
Axial computerised tomography characteristics of free fluid at delayed excretory phase. Arrows indicate contrast medium extravasation in the retroperitoneum.
Figure 3
Figure 3
Axial computerised tomography characteristics of urinoma at non contrast CT and delayed excretory phase. Arrows indicate encapsulated fluid collection surrounded by a fibrous capsule.
See this image and copyright information in PMC

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