Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Sep 17;22(18):10038.
doi: 10.3390/ijms221810038.

Metabolic Syndrome: From Molecular Mechanisms to Novel Therapies

Ali Abbas Rizvi  1   2 , Anca Pantea Stoian  3 , Manfredi Rizzo  2   3   4
Affiliations
Editorial

Metabolic Syndrome: From Molecular Mechanisms to Novel Therapies

Ali Abbas Rizvi et al. Int J Mol Sci. .

Abstract

The metabolic syndrome (MetS) consists of a cluster of metabolic abnormalities including central obesity, insulin resistance, glucose intolerance, hypertension, and atherogenic dyslipidemia [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare that this article has been written independently. APS is currently Vice President of Romanian National Diabetes Committee, and she has given lectures, received honoraria and research support, and participated in conferences, advisory boards, and clinical trials sponsored by many pharmaceutical companies including AstraZeneca, Boehringer Ingelheim, Medtronic, Eli Lilly, Merck, Novo Nordisk, Novartis, Roche Diagnostics, and Sanofi. MR is a full-time Professor of Internal Medicine at the University of Palermo, Italy, Editor in Chief of the International Journal of Molecular Sciences section Molecular Endocrinology and Metabolism, and currently Medical Director in Novo Nordisk Eastern Europe; he has given lectures, received honoraria and research support, and participated in conferences, advisory boards, and clinical trials sponsored by many pharmaceutical companies including Amgen, Astra Zeneca, Boehringer Ingelheim, Kowa, Eli Lilly, Meda, Mylan, Merck Sharp & Dohme, Novo Nordisk, Novartis, Roche Diagnostics, Sanofi, and Servier. None of the above-mentioned pharmaceutical companies had any role in this article, which has been written independently, without any financial or professional help, and reflects only the opinion of the authors, without any role of the industry.

References

    1. Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37:1595–1607. doi: 10.2337/diab.37.12.1595. - DOI - PubMed
    1. Kahn R., Buse J., Ferrannini E., Stern M. The Metabolic Syndrome: Time for a Critical Appraisal: Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2005;28:2289–2304. doi: 10.2337/diacare.28.9.2289. - DOI - PubMed
    1. Einhorn D., Reaven G.M., Cobin R.H., Ford E., Ganda O.P., Handelsman Y., Hellman R., Jellinger P.S., Kendall D., Krauss R.M., et al. American College of Endocrinology position statement on the insulin resistance syndrome. Endocr. Pr. 2003;9:237–252. - PubMed
    1. Ramzan F., Vickers M., Mithen R. Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review. Int. J. Mol. Sci. 2021;22:5047. doi: 10.3390/ijms22095047. - DOI - PMC - PubMed
    1. Abate N., Sallam H.S., Rizzo M., Nikolic D., Obradovic M., Bjelogrlic P., Isenovic E.R. Resistin: An inflamma-tory cytokine. Role in cardiovascular diseases, diabetes and the metabolic syndrome. Curr. Pharm. Des. 2014;20:4961–4969. doi: 10.2174/1381612819666131206103102. - DOI - PubMed

Publication types

MeSH terms