Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 May;27(5):515-20.
doi: 10.1136/gut.27.5.515.

Different HLA associated gene combinations contribute to susceptibility for coeliac disease and dermatitis herpetiformis

J A Sachs, J Awad, D McCloskey, C Navarrete, H Festenstein, E Elliot, J A Walker-Smith, C E Griffiths, J N Leonard, L Fry

Different HLA associated gene combinations contribute to susceptibility for coeliac disease and dermatitis herpetiformis

J A Sachs et al. Gut. 1986 May.

Abstract

Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac disease there was a significant increase in the frequencies of A1, B8, DR3, DR7, and DQw2 compared with controls but no increase of DR2. In dermatitis herpetiformis there were similarly increased frequencies of A1, B8, DR3, and DQw2. In contrast with coeliac disease, however, the frequency of DR7 (18%) was no different from the control group but there was an increased frequency of DR2.

PubMed Disclaimer

References

    1. Ann Hum Genet. 1955 Jun;19(4):251-3 - PubMed
    1. Immunol Rev. 1983;70:77-88 - PubMed
    1. Tissue Antigens. 1980 Mar;15(3):231-8 - PubMed
    1. J Clin Invest. 1972 Nov;51(11):2977-80 - PubMed
    1. J Immunol Methods. 1984 Oct 26;73(2):387-99 - PubMed

Publication types