The Urosepsis-A Literature Review
- PMID: 34577795
- PMCID: PMC8468212
- DOI: 10.3390/medicina57090872
The Urosepsis-A Literature Review
Abstract
Urosepsis is a very serious condition with a high mortality rate. The immune response is in the center of pathophysiology. The therapeutic management of these patients includes surgical treatment of the source of infection, antibiotic therapy and life support. The management of this pathology is multidisciplinary and requires good collaboration between the urology, intensive care, imaging and laboratory medicine departments. An imbalance of pro and anti-inflammatory cytokines produced during sepsis plays an important role in pathogenesis. The study of cytokines in sepsis has important implications for understanding pathophysiology and for development of other therapeutic solutions. If not treated adequately, urosepsis may lead to serious septic complications and organ sequelae, even to a lethal outcome.
Keywords: review; urosepsis.
Conflict of interest statement
The authors declare no conflict of interest.
References
-
- Reinhart K., Brunkhorst F.M., Bone H.-G., Bardutzky J., Dempfle C.-E., Forst H., Gastmeier P., Gerlach H., Gründling M., John S., et al. Prevention, diagnosis, therapy and follow-up care of sepsis: 1st revision of S-2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V. (DSG)) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin (DIVI)) Ger. Med. Sci. 2010;8 doi: 10.3205/000103. - DOI - PMC - PubMed
-
- Levy M.M., Artigas A., Phillips G.S., Rhodes A., Beale R., Osborn T., Vincent J.-L., Townsend S., Lemeshow S., Dellinger R.P. Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: A prospective cohort study. Lancet Infect. Dis. 2012;12:919–924. doi: 10.1016/S1473-3099(12)70239-6. - DOI - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical