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. 2021 Aug 28;13(9):3012.
doi: 10.3390/nu13093012.

The Association between Free Sugars Consumption and Laryngopharyngeal Reflux: A Cross-Sectional Study among Chinese Adolescents

Fang Li  1   2 , Qian Lin  3 , Qiping Yang  3 , Yue Xi  3 , Hanmei Liu  3 , Jing Luo  3 , Yufeng Ouyang  3 , Minghui Sun  3 , Cuiting Yong  3 , Caihong Xiang  3 , Jing Deng  1   2
Affiliations

The Association between Free Sugars Consumption and Laryngopharyngeal Reflux: A Cross-Sectional Study among Chinese Adolescents

Fang Li et al. Nutrients. .

Abstract

There is a lack of evidence to show prevalence of laryngopharyngeal reflux (LPR) and the association between LPR and dietary factors. Adolescents consume the most amount of free sugars among the Chinese population. We conducted this study to investigate the prevalence of LPR in Chinese adolescents and explore the association between free sugars consumption and LPR. A cross-sectional study was conducted on 1517 middle school students in Hunan, China. An online questionnaire was applied to collect data on the condition of LPR, consumption of free sugars and other self-reported covariates. Height, weight and waist circumference were collected by anthropometric measurements. Logistic regression was applied to assess the association between LPR and free sugars consumption. The mean and standard deviation of free sugars consumption was 53.14 ± 44.75 (g/d). The prevalence of LPR was 8.11%. A positive association was observed between LPR and higher free sugars consumption after adjusted multiple covariates, with adjusted odds ratio (95% confident interval) of 1.656 (1.125-2.438). The prevalence of LPR among Chinese adolescents was high. Further analytic studies with strict design are required to test the association between LPR and free sugar consumption. Systematic strategies and policies should to be developed to reduce the intake of free sugars in order to prevent LPR.

Keywords: Chinese adolescents; free sugars; laryngopharyngeal reflux.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
The receiver operating characteristic curve of the free sugars consumption and other covariates based on Model 4 of Table 3.
See this image and copyright information in PMC

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References

    1. Lechien J.R., Akst L.M., Hamdan A.L., Schindler A., Karkos P.D., Barillari M.R., Calvo-Henriquez C., Crevier-Buchman L., Finck C., Eun Y.G., et al. Evaluation and Management of Laryngopharyngeal Reflux Disease: State of the Art Review. Otolaryngol. Head Neck Surg. 2019;160:762–782. doi: 10.1177/0194599819827488. - DOI - PubMed
    1. Lechien J.R., Saussez S., Karkos P.D. Laryngopharyngeal reflux disease: Clinical presentation, diagnosis and therapeutic challenges in 2018. Curr. Opin. Otolaryngol. Head Neck Surg. 2018;26:392–402. doi: 10.1097/MOO.0000000000000486. - DOI - PubMed
    1. Yin C.Y., Zhang S.S., Zhong J.T., Zhou S.H. Pepsin and Laryngeal and Hypopharyngeal Carcinomas. Clin. Exp. Otorhinolaryngol. 2021;14:159–168. doi: 10.21053/ceo.2020.00465. - DOI - PMC - PubMed
    1. Ford C.N. Evaluation and management of laryngopharyngeal reflux. JAMA. 2005;294:1534–1540. doi: 10.1001/jama.294.12.1534. - DOI - PubMed
    1. Spantideas N., Drosou E., Bougea A., Assimakopoulos D. Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors. BMC Ear Nose Throat Disord. 2015;15:7. doi: 10.1186/s12901-015-0020-2. - DOI - PMC - PubMed

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