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. 2021 Oct;21(10):620-621.
doi: 10.1038/s41577-021-00602-2.

Gasdermins: making pores for pyroptosis

Feng Shao  1
Affiliations

Gasdermins: making pores for pyroptosis

Feng Shao. Nat Rev Immunol. 2021 Oct.
No abstract available

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References

Original articles
    1. Shi, J. et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526, 660–665 (2015) - DOI
    1. Kayagaki, N. et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526, 666–671 (2015) - DOI
Related articles
    1. Cookson, B. T. & Brennan, M. A. Pro-inflammatory programmed cell death. Trends Microbiol. 9, 113–114 (2001) - DOI
    1. Shi, J. et al. Pyroptosis: gasdermin-mediated programmed necrotic cell death. Trends Biochem. Sci. 42, 245–254 (2017) - DOI
    1. Zhou, Z. et al. Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells. Science 368, eaaz7548 (2020) - DOI

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