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. 2021 Oct;21(10):621.
doi: 10.1038/s41577-021-00617-9.

Checkpoint blockade: the end of the beginning

Jedd D Wolchok  1
Affiliations

Checkpoint blockade: the end of the beginning

Jedd D Wolchok. Nat Rev Immunol. 2021 Oct.
No abstract available

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References

Original articles
    1. Leach, D. R. et al. Enhancement of antitumor immunity by CTLA-4 blockade. Science 217, 1734–1736 (1996) - DOI
    1. Phan, G. Q. et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 100, 8372–8377 (2003) - DOI
    1. Hodi, F. S. et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc. Natl Acad. Sci. USA 100, 4712–4717 (2003) - DOI

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