Chronic lymphocytic leukaemia clones are detectable decades before diagnosis

Fie J Vojdeman¹, Jens Helby^{2

3

4}, Lone B Pedersen², Christian Brieghel², Michael A Andersen², Børge G Nordestgaard^{1

3

4

5}, Stig E Bojesen^{1

3

4

5}, Carsten U Niemann^{2

5}

Affiliations

¹ Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
² Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Herlev, Denmark.
³ The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
⁴ The Copenhagen City Heart Study, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Herlev, Denmark.
⁵ Institute for Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Herlev, Denmark.

Fie J Vojdeman et al. Br J Haematol. 2022 Feb.

. 2022 Feb;196(3):784-787.

doi: 10.1111/bjh.17857. Epub 2021 Sep 27.

Fie J Vojdeman¹, Jens Helby^{2

3

4}, Lone B Pedersen², Christian Brieghel², Michael A Andersen², Børge G Nordestgaard^{1

3

4

5}, Stig E Bojesen^{1

3

4

5}, Carsten U Niemann^{2

5}

¹ Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
² Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Herlev, Denmark.
³ The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
⁴ The Copenhagen City Heart Study, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Herlev, Denmark.
⁵ Institute for Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Herlev, Denmark.

No abstract available

References

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1. Nieto WG, Almeida J, Romero A, Teodosio C, López A, Henriques AF, et al. Increased frequency (12%) of circulating chronic lymphocytic leukemia-like B-cell clones in healthy subjects using a highly sensitive multicolor flow cytometry approach. Blood. 2009;114:33-7.
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