Aducanumab and the "post-amyloid" era of Alzheimer research?
- PMID: 34582783
- PMCID: PMC9308468
- DOI: 10.1016/j.neuron.2021.09.007
Aducanumab and the "post-amyloid" era of Alzheimer research?
Conflict of interest statement
Declaration of interests Dr. Musiek has provided consultation and has received research funding from Eisai Pharmaceuticals, the co-developer of aducanumab and developer of lecanemab. This interaction with Eisai is related to basic sleep research and is unrelated to aducanumab, lecanemab, or any other amyloid antibodies. No personal compensation was provided. Dr. Bennett has consulted for Takeda, Abbvie, Origent, and Vigorous Minds. He has received research funding from Biogen, the developer of aducanumab, for data analysis of data generated from his own group, and from Neurovision.
References
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- Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, and Wilson RS (2006). Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 66, 1837–1844. - PubMed
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- Haeberlein SB, von Hehn C, Chalkias S, Muralidharan KK, Chen T, Wu SY, Li J, Skordos L, Nisenbaum L, Rajagovindan R, et al. (2019). EMERGE and ENGAGE Topline Results: Two Phase 3 Studies to Evaluate Aducanumab in Patients With Early Alzheimer’s Disease.
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