Protein sorting: A new quality control pathway for GPI-anchored proteins
- PMID: 34582816
- DOI: 10.1016/j.cub.2021.08.039
Protein sorting: A new quality control pathway for GPI-anchored proteins
Abstract
Glycosylphosphatidylinositol-anchored proteins are a class of lipid-anchored membrane proteins found at the surface of all eukaryotic cells. New work provides genome-wide insights into mechanisms that mediate quality control of the folding of this important protein family.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Post-ER degradation of misfolded GPI-anchored proteins is linked with microautophagy.Curr Biol. 2021 Sep 27;31(18):4025-4037.e5. doi: 10.1016/j.cub.2021.06.078. Epub 2021 Jul 26. Curr Biol. 2021. PMID: 34314677
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