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. 2021 Jun 30;34(2):145-149.

Characteristics And Outcome Influence Of Increased Plasma Triglyceride Level In Severely Burned Adult Patients

N N Lam  1   2 , P Q Khanh  3 , N H An  1   2
Affiliations

Characteristics And Outcome Influence Of Increased Plasma Triglyceride Level In Severely Burned Adult Patients

N N Lam et al. Ann Burns Fire Disasters. .

Abstract
in English, French

The aims of this study were to investigate the profile of serum triglyceride level and its influence on outcomes in adult patients with severe burns. An observational study was conducted on 62 patients with burn extent from and over 20% TBSA. Results indicated that serum triglyceride level steadily increased from 1.9mmo/l on the 3rd day to 2.5 mmol/l on the 14th day before reducing on the 21st day after burn. Remarkably higher triglyceride level was seen in patients with full thickness burn area >20% TBSA and in inhalation injury (p < .05). Liver size significantly increased over time and was greater in increased triglyceride patients, but the difference was not significant (p > .05). In addition, patients with elevated serum triglyceride level had significantly higher rates of multiple organ failure and death compared with the remaining group. Further studies need to be conducted to understand and determine intervention for increased plasma triglyceride levels in severely burned patients.

Le but de cette étude était d’évaluer les triglycéridémies et leur influence sur le devenir d’adultes sévèrement brûlés. Il s’agit d’une étude observationnelle réalisée auprès de 62 patients brûlés sur > 20% SCT. La triglycéridémie augmente régulièrement, de 1,9 mmol/L à J3 jusqu’à 2,5 mmol/L à J14 pour diminuer à partir de J21. Des taux particulièrement élevés étaient observés en cas d’atteinte profonde et d’inhalation de fumées (p < 0,05). La taille du foie augmentait au cours du temps et semblait plus élevés chez les patients hypertriglycéridémiques, sans être significative. En outre, les patients hypertriglycéridémiques développaient plus fréquemment une défaillance multiviscérale et leur mortalité était plus élevée. D’autres études sont nécessaires pour comprendre le mécanisme de cette hypertriglycéridémie et proposer une conduite à tenir pour ces patients.

Keywords: adult burn; outcomes; serum triglyceride.

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Figures

Table I
Table I. Patient demographic (n = 62)
Table II
Table II. Serum TG level along the time after burns
Table III
Table III. Distribution of plasma TG level (mmol/l) to patients and burn features
Table IV
Table IV. Relationship between TG level and liver size (n = 34)
Table V
Table V. Relationship between TG level (mmol/l) and outcomes
See this image and copyright information in PMC

References

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