Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 May;63(1):51-7.
doi: 10.1111/j.1365-2141.1986.tb07494.x.

Increased frequency of DR2 in patients with aplastic anaemia and increased DR sharing in their parents

B Chapuis, V E Von Fliedner, M Jeannet, H Merica, P Vuagnat, A Gratwohl, C Nissen, B Speck

Increased frequency of DR2 in patients with aplastic anaemia and increased DR sharing in their parents

B Chapuis et al. Br J Haematol. 1986 May.

Abstract

68 patients with aplastic anaemia, their parents and healthy siblings were typed for HLA-A, B and DR antigens. Among the patients there is an overrepresentation of DR2. The parents of affected children show an increased compatibility at the DR locus. This situation could favour the expression of recessive gene(s) involved in haematopoiesis and located in the HLA locus.

PubMed Disclaimer

Publication types

LinkOut - more resources