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Meta-Analysis
. 2021 Sep 18:2021:7751516.
doi: 10.1155/2021/7751516. eCollection 2021.

Extraction vs. Nonextraction on Soft-Tissue Profile Change in Patients with Malocclusion: A Systematic Review and Meta-Analysis

SangYoun Moon  1 , Abdelrahman Magdi Ahmd Mohamed  1 , YaLi He  1 , WenJie Dong  1 , Chen Yaosen  1 , Yan Yang  1
Affiliations
Meta-Analysis

Extraction vs. Nonextraction on Soft-Tissue Profile Change in Patients with Malocclusion: A Systematic Review and Meta-Analysis

SangYoun Moon et al. Biomed Res Int. .

Abstract

Objectives: We aimed to summarize the current evidence regarding the impact of extraction vs. nonextraction in orthodontic treatment on patients' soft-tissue profile with malocclusion.

Methods: Between April 30th and November 30th, 2020, we searched PubMed and SCOPUS for published papers from inception to November 2020 using "orthodontic," "extraction," "nonextraction," and "Malocclusion." Included studies were summarized, and relevant data were extracted and analyzed using Review Manager 5.4.

Results: Pooled data from four controlled trials demonstrated a nonsignificant difference between extraction and nonextraction in terms of SNA (MD = 0.50, 95% CI: -0.37, 1.38; p = 0.26), SNB (MD = 0.11, 95% CI: -1.23, 1.44; p = 0.88), FMA (MD = 1.82, 95% CI: -2.39, 6.02; p = 0.40), IMPA (MD = 0.06, 95% CI: -8.83, -8.94; p = 0.99), overjet (MD = -1.47, 95% CI: -6.21, 3.26; p = 0.54), and overbite (MD = 0.50, 95% CI: -1.40, 2.40; p = 0.60). On the other hand, the extraction method significantly increased the ANB compared with the nonextraction group (MD = 0.78, 95% CI: 0.25, 1.31; p = 0.004).

Conclusion: The current evidence demonstrated that nonextraction protocols for orthodontic treatment are a safe and effective alternative to extraction protocols; individually tailored treatment strategies should be applied. More randomized controlled trials are critically needed to safely make an evidence-based treatment conclusion.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
The PRISMA flow diagram.
Figure 2
Figure 2
Summary of the risk of bias of included studies.
Figure 3
Figure 3
(a–c) The heterogeneity and test for overall effect.
Figure 4
Figure 4
(a–d) The heterogeneity and test for overall effect.
Figure 5
Figure 5
(a–c) The heterogeneity and test for overall effect.
See this image and copyright information in PMC

References

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